Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | PKLR | P30613 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.45 |
| ▸ | ITGAL | P20701 | 1/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22288107 | 1.00 | PTPRA (0.75) | PTPRACYP2C19PKMPKLRMAPT | |
| SCHEMBL22288108 | 1.00 | PTPRA (0.75) | PTPRACYP2C19PKMPKLRMAPT | |
| SCHEMBL5773295 | 0.91 | PTPRA (0.61) | PTPRACYP2C19MAPTALDH1A1NQO2 | |
| SCHEMBL4113355 | 0.91 | PTPRA (0.61) | PTPRACYP2C19MAPTALDH1A1NQO2 | |
| SCHEMBL7380735 | 0.90 | PTPRA (0.73) | PTPRACYP2C19PKMPKLRMAPT | |
| SCHEMBL30789181 | 0.86 | PTPRA (1.00) | PTPRACYP2C19PKMPKLRMAPT | |
| SCHEMBL3519524 | 0.86 | PTPRA (1.00) | PTPRACYP2C19PKMPKLRMAPT | |
| SCHEMBL145392 | 0.86 | PTPRA (1.00) | PTPRACYP2C19PKMPKLRMAPT | |
| SCHEMBL30381729 | 0.86 | PTPRA (1.00) | PTPRACYP2C19PKMPKLRMAPT | |
| SCHEMBL2965137 | 0.86 | PTPRA (1.00) | PTPRACYP2C19PKMPKLRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230057350-A1 | A CONJUGATE OF AN AMANITA TOXIN WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-02-23 | — | — | US | disclosed |
| WO-2019078498-A1 | AMATOXIN DERIVATIVE AND PREPARATION METHOD THEREFOR | 한국화학연구원 | 2019-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230057350-A1 | A CONJUGATE OF AN AMANITA TOXIN WITH BRANCHED LINKERS | BTN3A1, ANTXR2, CLTA | PTPRA 845/4885CYP2C19 4855/4885PKM 4031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.