Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PKLR | P30613 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22288107 | 0.90 | PTPRA (0.75) | PTPRACYP2C19SCN9APKMPKLR | |
| SCHEMBL22288108 | 0.90 | PTPRA (0.75) | PTPRACYP2C19SCN9APKMPKLR | |
| SCHEMBL20931031 | 0.90 | PTPRA (0.75) | PTPRACYP2C19SCN9APKMPKLR | |
| SCHEMBL3519524 | 0.85 | PTPRA (1.00) | PTPRACYP2C19SCN9APKMPKLR | |
| SCHEMBL30789181 | 0.85 | PTPRA (1.00) | PTPRACYP2C19SCN9APKMPKLR | |
| SCHEMBL30381729 | 0.85 | PTPRA (1.00) | PTPRACYP2C19SCN9APKMPKLR | |
| SCHEMBL145392 | 0.85 | PTPRA (1.00) | PTPRACYP2C19SCN9APKMPKLR | |
| SCHEMBL2965137 | 0.85 | PTPRA (1.00) | PTPRACYP2C19SCN9APKMPKLR | |
| SCHEMBL16366296 | 0.82 | PTPRA (0.73) | PTPRACYP2C19PKMPKLRMAPT | |
| SCHEMBL22316600 | 0.82 | PTPRA (0.73) | PTPRACYP2C19PKMPKLRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010077-A | Tranquilizers | A/S FERROSAN (DK) | 1991-04-23 | — | — | US | disclosed |
| EP-0030254-B1 | BETA-CARBOLIN-3-CARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR THERAPEUTICAL USE | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-10-31 | — | — | EP | disclosed |
| US-4371536-A | TRANQUILIZERS | A/S FERROSAN (DK) | 1983-02-01 | — | — | US | disclosed |
| EP-0030254-A1 | Beta-carbolin-3-carboxylic acid derivatives, pharmaceutical compositions containing them and their therapeutical use | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-06-17 | — | — | EP | disclosed |