SCHEMBL20933100

SCHEMBL20933100

Cc1ccc(-c2cccc3c2[nH]c2ccc(-c4ccccc4)cc23)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.50
CDK4 P11802 6/20 0.48
CCND1 P24385 6/20 0.48
CCNB2 O95067 1/20 0.48
CCNE2 O96020 1/20 0.48
CDK1 P06493 1/20 0.48
CCNB1 P14635 1/20 0.48
CCNE1 P24864 1/20 0.48
CDK2 P24941 1/20 0.48
CCNB3 Q8WWL7 1/20 0.48
PARP14 Q460N5 3/20 0.44
KIF11 P52732 1/20 0.42
HPGD P15428 3/20 0.42
KDM4E B2RXH2 2/20 0.42
RAB9A P51151 2/20 0.42
CTSV O60911 1/20 0.42
CTSL P07711 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17040549 0.92 CDK4 (0.54) BCHECDK4CCND1CCNB2CCNE2
SCHEMBL31285499 0.92 CDK4 (0.54) BCHECDK4CCND1CCNB2CCNE2
SCHEMBL28421443 0.88 BCHE (0.50) BCHECDK4CCND1HPGDKDM4E
SCHEMBL30772431 0.86 KIF11 (0.58) PARP14KIF11HPGDKDM4ERAB9A
SCHEMBL20933871 0.86 KIF11 (0.58) PARP14KIF11HPGDKDM4ERAB9A
SCHEMBL28841109 0.85 GABRP (0.47) CDK4CCND1CCNB2CCNE2CDK1
SCHEMBL20933270 0.85 KIF11 (0.50) BCHECDK4CCND1CCNB2CCNE2
SCHEMBL20933098 0.84 BCHE (0.53) BCHECDK4CCND1KIF11HPGD
SCHEMBL26551012 0.84 PARP14 (0.49) BCHECDK4CCND1CCNB2CCNE2
SCHEMBL21412954 0.83 BCHE (0.51) BCHECDK4CCND1CCNB2CCNE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019078461-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2019-04-25 WO disclosed