SCHEMBL20933643

SCHEMBL20933643

COC(=O)c1ccccc1-c1cccc2c1Oc1cc(Cl)ccc1O2

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 4/20 0.51
SLC6A4 P31645 3/20 0.51
TRPA1 O75762 2/20 0.44
ALOX5 P09917 2/20 0.43
HSD17B3 P37058 1/20 0.41
ABL1 P00519 1/20 0.41
AHR P35869 2/20 0.41
SLC6A2 P23975 1/20 0.40
PDK2 Q15119 1/20 0.40
ALDH1A1 P00352 2/20 0.39
NPC1 O15118 1/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LTB4R Q15722 1/20 0.39
LTB4R2 Q9NPC1 1/20 0.39
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20933679 1.00 SLC6A3 (0.51) SLC6A3SLC6A4TRPA1ALOX5HSD17B3
SCHEMBL20934245 0.89 ALOX5 (0.52) SLC6A3SLC6A4TRPA1ALOX5SLC6A2
SCHEMBL20934474 0.84 SLC6A3 (0.50) SLC6A3SLC6A4TRPA1ALOX5AHR
SCHEMBL20934267 0.83 SLC6A3 (0.49) SLC6A3SLC6A4TRPA1ALOX5AHR
SCHEMBL19058193 0.79 SLC6A3 (0.55) SLC6A3SLC6A4ALOX5HSD17B3ABL1
SCHEMBL16724065 0.78 PDK2 (0.42) SLC6A3SLC6A4TRPA1ALOX5HSD17B3
SCHEMBL19058260 0.78 SLC6A3 (0.56) SLC6A3SLC6A4ALOX5HSD17B3ABL1
SCHEMBL16724062 0.77 SLC6A4 (0.43) SLC6A3SLC6A4TRPA1ALOX5ABL1
SCHEMBL16724069 0.76 SLC6A3 (0.42) SLC6A3SLC6A4TRPA1ALOX5ABL1
SCHEMBL20933642 0.74 AHR (0.44) SLC6A3SLC6A4AHRSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019078461-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2019-04-25 WO disclosed