Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.40 |
| ▸ | STK10 | O94804 | 1/20 | 0.31 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19011255 | 0.91 | PDK2 (0.41) | PDK2MEN1ALDH1A1ARMAPT | |
| SCHEMBL24968708 | 0.87 | PDK2 (0.44) | PDK2MEN1ALDH1A1ARMAPT | |
| SCHEMBL22182353 | 0.86 | PDK2 (0.35) | PDK2MEN1ALDH1A1ARMAPT | |
| SCHEMBL24969298 | 0.85 | PDK2 (0.42) | PDK2STK10SLKCNR1BRD4 | |
| SCHEMBL20346073 | 0.84 | PDK2 (0.41) | PDK2MEN1ALDH1A1ARMAPT | |
| SCHEMBL24406663 | 0.84 | PDK2 (0.44) | PDK2MEN1ALDH1A1ARMAPT | |
| SCHEMBL25657121 | 0.84 | PDK2 (0.47) | PDK2STK10SLKMEN1ALDH1A1 | |
| SCHEMBL30721691 | 0.84 | PDK2 (0.47) | PDK2STK10SLKMEN1ALDH1A1 | |
| SCHEMBL24969757 | 0.84 | PDK2 (0.43) | PDK2STK10SLKMEN1ALDH1A1 | |
| SCHEMBL20935760 | 0.84 | PDK2 (0.46) | PDK2STK10SLKCNR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961230-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2021-03-30 | — | — | US | disclosed |
| US-20190119260-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10961230-B2 | Materials for organic electroluminescent devices | DDT, PNMT, INMT | PDK2 778/4885STK10 3783/4885SLK 3749/4885 |
| US-20190119260-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | DDT, PNMT, INMT | PDK2 778/4885STK10 3783/4885SLK 3749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.