SCHEMBL20936201

SCHEMBL20936201

CC(C)(C)c1cscc1CC(C)(C)c1cnc[nH]1

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22908841 0.78 HRH4 (0.31) HRH4
SCHEMBL14415970 0.67 HRH4 (0.44) HRH4
SCHEMBL20696522 0.66 HPGD (0.42) HRH4
SCHEMBL22343509 0.66 HRH4 (0.36) HRH4
Hydrochloric Acid SCHEMBL25371613 0.65 HRH4 (0.43) HRH4
SCHEMBL14857108 0.65 HRH4 (0.43) HRH4
SCHEMBL23713601 0.64
SCHEMBL26052366 0.64 HRH1 (0.42) HRH4
SCHEMBL16264708 0.64 HRH4 (0.42) HRH4
SCHEMBL26812529 0.64 HRH4 (0.42) HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10640511-B2 Hepatitis B antiviral agents Enant Pharmaceuticals, Inc. (US) 2020-05-05 US disclosed
US-20190119288-A1 HEPATITIS B ANTIVIRAL AGENTS ENANTA PHARM INC (US) 2019-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190119288-A1 HEPATITIS B ANTIVIRAL AGENTS HAVCR2, SLC10A1, HDGF HRH4 2991/4885
US-10640511-B2 Hepatitis B antiviral agents HAVCR2, SLC10A1, HDGF HRH4 2991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.