Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 5/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20937417 | 0.97 | MAPK1 (0.38) | CYP11B2CYP11B1CYP19A1CYP17A1MAPK1 | |
| SCHEMBL20937424 | 0.94 | CYP3A4 (0.40) | CYP11B2CYP11B1CYP19A1CYP17A1MAPK1 | |
| SCHEMBL20937425 | 0.93 | MAPT (0.40) | CYP11B2CYP11B1CYP19A1CYP17A1MAPK1 | |
| SCHEMBL20937719 | 0.92 | CYP11B2 (0.40) | CYP11B2CYP11B1CYP19A1CYP17A1MAPK1 | |
| SCHEMBL20937426 | 0.92 | CYP11B2 (0.39) | CYP11B2CYP11B1CYP19A1CYP17A1MAPK1 | |
| SCHEMBL20937381 | 0.92 | PDE5A (0.43) | CYP11B2CYP11B1CYP19A1CYP17A1MAPK1 | |
| SCHEMBL20937406 | 0.91 | CYP11B1 (0.43) | CYP11B2CYP11B1CYP19A1CYP17A1MAPK1 | |
| SCHEMBL20937436 | 0.91 | MAPT (0.38) | CYP11B2CYP11B1CYP19A1CYP17A1MAPK1 | |
| SCHEMBL20937430 | 0.91 | CYP3A4 (0.41) | CYP11B2CYP11B1CYP19A1CYP17A1MAPK1 | |
| SCHEMBL20937437 | 0.90 | MAPT (0.41) | CYP11B2CYP11B1CYP19A1CYP17A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019076844-A1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-04-25 | — | — | WO | disclosed |