Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20937436 | 0.97 | MAPT (0.38) | CYP11B2CYP19A1CYP11B1CYP17A1CYP3A4 | |
| SCHEMBL20937423 | 0.94 | CYP3A4 (0.40) | CYP11B2CYP19A1CYP11B1CYP17A1CYP3A4 | |
| SCHEMBL20937402 | 0.93 | MAPT (0.40) | CYP11B2CYP19A1CYP11B1CYP17A1CYP3A4 | |
| SCHEMBL20937410 | 0.92 | CYP11B2 (0.38) | CYP11B2CYP19A1CYP11B1CYP17A1CYP3A4 | |
| SCHEMBL20937727 | 0.92 | CYP11B2 (0.41) | CYP11B2CYP19A1CYP11B1CYP17A1CYP3A4 | |
| SCHEMBL20937368 | 0.92 | MAPT (0.41) | CYP11B2CYP19A1CYP11B1CYP17A1CYP3A4 | |
| SCHEMBL20937433 | 0.91 | CYP11B1 (0.43) | CYP11B2CYP19A1CYP11B1CYP17A1CYP3A4 | |
| SCHEMBL20937417 | 0.91 | MAPK1 (0.38) | CYP11B2CYP19A1CYP11B1CYP17A1CYP3A4 | |
| SCHEMBL20937431 | 0.90 | MAPT (0.41) | CYP11B2CYP19A1CYP11B1CYP17A1CYP3A4 | |
| SCHEMBL20937379 | 0.89 | MAPT (0.39) | CYP11B2CYP19A1CYP11B1CYP17A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019076844-A1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-04-25 | — | — | WO | disclosed |