Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18572160 | 0.85 | CA12 (0.38) | CA12CA1CA2CA9 | |
| SCHEMBL23136584 | 0.79 | CA12 (0.34) | CA12CA1CA2CA9 | |
| SCHEMBL22679765 | 0.79 | CA12 (0.34) | CA12CA1CA2CA9 | |
| SCHEMBL21099442 | 0.75 | CA12 (0.32) | CA12CA1CA2CA9 | |
| SCHEMBL18572159 | 0.73 | CA12 (0.35) | CA12CA1CA2CA9 | |
| SCHEMBL3261185 | 0.73 | — | — | |
| SCHEMBL30008586 | 0.71 | L3MBTL1 (0.35) | CA12CA1CA2CA9 | |
| SCHEMBL1648797 | 0.67 | CA12 (0.42) | CA12CA1CA2CA9 | |
| SCHEMBL1648800 | 0.67 | CA12 (0.42) | CA12CA1CA2CA9 | |
| Iodide SCHEMBL3908349 | 0.66 | CA12 (0.41) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019079783-A1 | ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY (US) | 2019-04-25 | — | — | WO | disclosed |