Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12282802 | 1.00 | TAAR1 (0.54) | TAAR1AOC3HPGDALDH1A1TRPA1 | |
| SCHEMBL1911097 | 1.00 | TAAR1 (0.54) | TAAR1AOC3HPGDALDH1A1TRPA1 | |
| SCHEMBL6058476 | 0.87 | L3MBTL1 (0.38) | TAAR1HPGDALDH1A1MAPT | |
| SCHEMBL17084205 | 0.86 | TAAR1 (0.45) | TAAR1AOC3HPGDALDH1A1TRPA1 | |
| SCHEMBL29445793 | 0.86 | TAAR1 (0.45) | TAAR1AOC3HPGDALDH1A1TRPA1 | |
| SCHEMBL17086756 | 0.86 | TAAR1 (0.45) | TAAR1AOC3HPGDALDH1A1TRPA1 | |
| SCHEMBL3632312 | 0.83 | TAAR1 (0.56) | TAAR1AOC3ALDH1A1TRPA1RIPK1 | |
| SCHEMBL585216 | 0.83 | TAAR1 (0.56) | TAAR1AOC3ALDH1A1TRPA1RIPK1 | |
| SCHEMBL8235389 | 0.82 | RIPK1 (0.53) | TAAR1AOC3HPGDALDH1A1TRPA1 | |
| SCHEMBL22050524 | 0.82 | TAAR1 (0.50) | TAAR1AOC3HPGDALDH1A1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34640-E | Polymerizing isobutylene, adding monomer to make block polymer; metal halide, initiator and electron pair doner solvent | UNIVERSITY OF AKRON (US) | 1994-06-14 | — | — | US | claimed |
| WO-1991011468-A1 | NEW THERMOPLASTIC ELASTOMERS | THE UNIVERSITY OF AKRON (US) | 1991-08-08 | — | — | WO | claimed |
| US-4946899-A | CARBOCATIONIC POLYMERIZATION INVOLVING HOMOPOLYMERIZATION OF ELASTOMER FOLLOWED BY COPOLYMERIZATION TO ADD GLASSY SEGMENTS; FORMING LIVING POLYMERS WITH A METAL HALIDE, PROMOTER AND SOLVENT MIXTURE | THE UNIVERSITY OF AKRON (US) | 1990-08-07 | — | — | US | claimed |
| WO-2024137607-A1 | THIADIAZOLE DERIVATIVES AS INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024005209-A1 | 1,4-CINEOLE DERIVATIVE AND INTERMEDIATE THEREOF, HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT, METHOD FOR USING HERBICIDE, AND METHOD FOR PREPARING AGROCHEMICAL COMPOSITION | 北興化学工業株式会社 | 2024-01-04 | — | — | WO | disclosed |
| EP-3262036-B1 | THERAPEUTIC PYRIDAZINE COMPOUNDS AND USES THEREOF | GENENTECH INC (US) | 2023-09-13 | — | — | EP | disclosed |
| EP-3466929-B1 | HETEROCYCLIC COMPOUNDS USEFUL AS PDK1 INHIBITORS | MILLENNIUM PHARM INC (US) | 2023-09-06 | — | — | EP | disclosed |
| CN-116478350-A | Poly (isomonoolefin) copolymer and application thereof | 北京石油化工学院 | 2023-07-25 | — | — | CN | disclosed |
| CN-116425930-A | Poly (isomonoolefin) copolymer, initiator system and application | 北京石油化工学院 | 2023-07-14 | — | — | CN | disclosed |
| WO-2023072966-A1 | IMIDAZOLONE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES IN PARTICULAR DYRK1A, CLK1 AND/OR CLK4 | PERHA PHARMACEUTICALS (FR) | 2023-05-04 | — | — | WO | disclosed |
| US-20230019032-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | US | disclosed |
| US-20080020275-A1 | noncrystalline fluorine containing polyethers; perfluoropolyethers; high molecular weight, high ionic conductivity at room temperature, low viscosity, nonflammable, oxidation resistance; for use as electrolyte of lithium secondary batteries, capacitors, and solar cells | DAIKIN INDUSTRIES, LTD. (JP) | 2008-01-24 | — | — | US | disclosed |
| US-20070190314-A1 | Transparent article and method for producing it, and lens substrate | FUJIFILM CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| US-RE39746-E1 | Phosphoric esters and their use as dispersants | GOLDSCHMIDT GMBH (DE) | 2007-07-31 | — | — | US | disclosed |
| US-7163997-B2 | Polyether derivative and process for producing the same | FUJI PHOTO FILM CO., LTD. (JP) | 2007-01-16 | — | — | US | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| EP-1033364-B1 | Cyano containing oxamic acids and derivatives as thyroid receptor ligands | PFIZER PROD INC (US) | 2005-02-23 | — | — | EP | disclosed |
| US-6194454-B1 | ANTILIPEMIC AGENTS; ANTIDIABETIC AGENTS; DIETETICS; RHEUMATIC DISEASES; ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS; ANTIDEPRESSANTS; BONE DISORDERS | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| EP-1033364-A1 | Cyano containing oxamic acids and derivatives as thyroid receptor ligands | Pfizer Products Inc. (US) | 2000-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230019032-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | MAPK1, ALK, MAP3K1 | TAAR1 685/4885AOC3 1363/4885HPGD 3679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.