Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 3/20 | 0.39 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19120374 | 0.85 | ADK (0.54) | PRMT5ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL10266132 | 0.85 | ADK (0.54) | PRMT5ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL18571875 | 0.84 | ADK (0.53) | PRMT5ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL20938334 | 0.84 | METTL3 (0.43) | PRMT5ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL13349028 | 0.84 | ADK (0.53) | PRMT5WDR77ALDH1A1LMNAALB | |
| SCHEMBL13065028 | 0.84 | ADK (0.53) | PRMT5ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL12993150 | 0.84 | ADK (0.53) | PRMT5WDR77ALDH1A1LMNAALB | |
| SCHEMBL13065176 | 0.84 | ADK (0.53) | PRMT5WDR77ALDH1A1LMNAALB | |
| SCHEMBL10265019 | 0.82 | ADK (0.54) | ALDH1A1LMNAALBMAPK1ADK | |
| SCHEMBL20938429 | 0.81 | PRMT5 (0.50) | PRMT5WDR77ALDH1A1METTL3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019076633-A1 | NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF PARASITIC INFECTIONS | UNIVERSITEIT GENT (BE) | 2019-04-25 | — | — | WO | disclosed |