Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 20/20 | 0.57 |
| ▸ | WNT1 | P04628 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20938609 | 0.86 | GSK3B (0.61) | GSK3BDYRK1A | |
| SCHEMBL20938515 | 0.82 | GSK3B (0.61) | GSK3BDYRK1A | |
| SCHEMBL20938716 | 0.78 | GSK3B (0.49) | GSK3BDYRK1AWNT1 | |
| SCHEMBL23741354 | 0.76 | GSK3B (0.59) | GSK3BDYRK1AWNT1 | |
| SCHEMBL23916195 | 0.76 | HCAR3 (0.36) | GSK3BDYRK1AWNT1 | |
| SCHEMBL23740978 | 0.75 | GSK3B (0.62) | GSK3BDYRK1AWNT1 | |
| SCHEMBL20938707 | 0.75 | GSK3B (0.59) | GSK3BDYRK1AWNT1 | |
| SCHEMBL24219674 | 0.75 | GSK3B (0.61) | GSK3BDYRK1AWNT1 | |
| SCHEMBL20938487 | 0.75 | GSK3B (0.62) | GSK3BDYRK1AWNT1 | |
| SCHEMBL23741125 | 0.74 | DYRK1A (0.59) | GSK3BDYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019079626-A1 | 6-(5-MEMBERED HETEROARYL)ISOQUINOLIN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF | SAMUMED, LLC (US) | 2019-04-25 | — | — | WO | disclosed |