SCHEMBL2093906

SCHEMBL2093906

[CH2]Oc1ccc(CC=C)cc1OC

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.83
▸ PPARA Q07869 3/20 0.83
▸ PPARG P37231 1/20 0.83
▸ PPARD Q03181 1/20 0.83
▸ PTGS1 P23219 2/20 0.65
▸ CYP3A4 P08684 3/20 0.65
▸ ALOX5 P09917 2/20 0.65
▸ AR P10275 1/20 0.65
▸ TRPM8 Q7Z2W7 1/20 0.65
▸ SMN1; SMN2 Q16637 5/20 0.63
▸ MAPT P10636 4/20 0.63
▸ MEN1 O00255 3/20 0.63
▸ KMT2A Q03164 3/20 0.63
▸ LMNA P02545 2/20 0.63
▸ GAA P10253 2/20 0.63
▸ KDM4E B2RXH2 1/20 0.63
▸ HTT P42858 1/20 0.63
▸ TDP1 Q9NUW8 2/20 0.58
▸ L3MBTL1 Q9Y468 2/20 0.58
▸ GABRA1 P14867 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyleugenol SCHEMBL29376951 0.91 ALDH1A1 (1.00) ALDH1A1PPARAPPARGPPARDPTGS1
Methyleugenol SCHEMBL1869396 0.91 ALDH1A1 (1.00) ALDH1A1PPARAPPARGPPARDPTGS1
Methyleugenol SCHEMBL113794 0.91 ALDH1A1 (1.00) ALDH1A1PPARAPPARGPPARDPTGS1
Methyleugenol SCHEMBL27951383 0.89 ALDH1A1 (0.96) ALDH1A1PPARAPPARGPPARDPTGS1
Methyleugenol SCHEMBL27600712 0.89 ALDH1A1 (0.96) ALDH1A1PPARAPPARGPPARDPTGS1
Methyleugenol SCHEMBL5564539 0.89 ALDH1A1 (0.96) ALDH1A1PPARAPPARGPPARDPTGS1
SCHEMBL1870530 0.87 ALDH1A1 (0.86) ALDH1A1PPARAPPARGPPARDPTGS1
Methyleugenol SCHEMBL28067388 0.87 ALDH1A1 (0.93) ALDH1A1PPARAPPARGPPARDPTGS1
SCHEMBL4353980 0.87 ALDH1A1 (0.86) ALDH1A1PPARAPPARGPPARDPTGS1
SCHEMBL7233407 0.84 ALDH1A1 (0.80) ALDH1A1PPARAPPARGPPARDPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4059348-A1 MIXTURE OF A FOLCYSTEINE-BASED BIOSTIMULANT AND AN AGROTOXIC SUBSTANCE OF INTEREST RESULTING IN A QUANTITATIVELY, QUALITATIVELY AND TIME-RELATED RESULT-POTENTIATING ACTION AS OBSERVED IN AN AGRICULTURAL CROP OF A PLANT OF INTEREST UPL Corporation Limited (MU) 2022-09-21 — — EP claimed
US-20220279784-A1 Mixture of a Folcysteine-Based Biostimulant and an Agrotoxic Substance of Interest Resulting in a Quantitatively, Qualitatively and Time-Related Result-potentiating Action as Observed in an Agricultural Crop of a Plant of Interest UPL Corporation Limited (MU) 2022-09-08 — — US claimed
US-20200337305-A1 Mixture of a Folcysteine-based Biostimulant and an Agrotoxic Substance of Interest Resulting in a Quantitatively, Qualitatively and Time-related Result-potentiating Action as Observed in an Agricultural Crop of a Plant of Interest UPL Corporation Limited (MU) 2020-10-29 — — US claimed
EP-3679796-A1 MIXTURE OF A FOLCYSTEINE-BASED BIOSTIMULANT AND AN AGROTOXIC SUBSTANCE OF INTEREST RESULTING IN A QUANTITATIVELY, QUALITATIVELY AND TIME-RELATED RESULT-POTENTIATING ACTION AS OBSERVED IN AN AGRICULTURAL CROP OF A PLANT OF INTEREST UPL Corporation Limited (MU) 2020-07-15 — — EP claimed
EP-4059348-A1 MIXTURE OF A FOLCYSTEINE-BASED BIOSTIMULANT AND AN AGROTOXIC SUBSTANCE OF INTEREST RESULTING IN A QUANTITATIVELY, QUALITATIVELY AND TIME-RELATED RESULT-POTENTIATING ACTION AS OBSERVED IN AN AGRICULTURAL CROP OF A PLANT OF INTEREST UPL Corporation Limited (MU) 2022-09-21 — — EP disclosed
US-20220279784-A1 Mixture of a Folcysteine-Based Biostimulant and an Agrotoxic Substance of Interest Resulting in a Quantitatively, Qualitatively and Time-Related Result-potentiating Action as Observed in an Agricultural Crop of a Plant of Interest UPL Corporation Limited (MU) 2022-09-08 — — US disclosed
US-11388900-B2 Mixture of a folcysteine-based biostimulant and an agrotoxic substance of interest resulting in a quantitatively, qualitatively and time-related result-potentiating action as observed in an agricultural crop of a plant of interest UPL Corporation Limited (MU) 2022-07-19 — — US disclosed
US-20200337305-A1 Mixture of a Folcysteine-based Biostimulant and an Agrotoxic Substance of Interest Resulting in a Quantitatively, Qualitatively and Time-related Result-potentiating Action as Observed in an Agricultural Crop of a Plant of Interest UPL Corporation Limited (MU) 2020-10-29 — — US disclosed
EP-3679796-A1 MIXTURE OF A FOLCYSTEINE-BASED BIOSTIMULANT AND AN AGROTOXIC SUBSTANCE OF INTEREST RESULTING IN A QUANTITATIVELY, QUALITATIVELY AND TIME-RELATED RESULT-POTENTIATING ACTION AS OBSERVED IN AN AGRICULTURAL CROP OF A PLANT OF INTEREST UPL Corporation Limited (MU) 2020-07-15 — — EP disclosed
US-8163753-B2 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2012-04-24 — — US disclosed
EP-1678185-B1 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMA CO LTD (JP) 2008-10-08 — — EP disclosed
US-20080119478-A1 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis OTSUKA PHAMACEUTICAL CO., LTD. (JP) 2008-05-22 — — US disclosed
EP-1678185-A1 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-07-12 — — EP disclosed
WO-2005042542-A1 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-05-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080119478-A1 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis NR2C2, NR0B2, NR4A2 ALDH1A1 412/4885PPARA 337/4885PPARG 457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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