SCHEMBL20943333

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20943329	1.00	ALDH1A1 (0.51)	ALDH1A1MAPK1L3MBTL1SLC15A1EPHX2
	SCHEMBL22483207	0.98	ALDH1A1 (0.53)	ALDH1A1MAPK1L3MBTL1SLC15A1EPHX2
	SCHEMBL20960093	0.94	ALDH1A1 (0.54)	ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A
	SCHEMBL20943396	0.93	MEN1 (0.55)	ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A
	SCHEMBL20943380	0.93	MEN1 (0.55)	ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A
	SCHEMBL20943382	0.90	ALDH1A1 (0.55)	ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A
	SCHEMBL3409158	0.90	MEN1 (0.52)	ALDH1A1KMT2AMEN1HPGDFOLH1
	SCHEMBL20943371	0.88	MMP3 (0.47)	ALDH1A1MAPK1L3MBTL1SLC15A1EPHX2
	SCHEMBL8491358	0.88	ALDH1A1 (0.57)	ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A
	SCHEMBL4941879	0.87	ALDH1A1 (0.66)	ALDH1A1MAPK1L3MBTL1EPHX2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.