Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20943360 | 1.00 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPK1EPHX2LMNA | |
| SCHEMBL22465770 | 0.99 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MAPK1EPHX2LMNA | |
| SCHEMBL24678178 | 0.97 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MAPK1EPHX2LMNA | |
| SCHEMBL24678051 | 0.97 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MAPK1EPHX2LMNA | |
| SCHEMBL24678110 | 0.97 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MAPK1EPHX2LMNA | |
| SCHEMBL24678074 | 0.97 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MAPK1EPHX2LMNA | |
| SCHEMBL20943365 | 0.95 | MBOAT4 (0.46) | ALDH1A1L3MBTL1MAPK1EPHX2MBOAT4 | |
| SCHEMBL20943336 | 0.95 | MBOAT4 (0.46) | ALDH1A1L3MBTL1MAPK1EPHX2MBOAT4 | |
| SCHEMBL17381294 | 0.95 | MBOAT4 (0.46) | ALDH1A1L3MBTL1MAPK1EPHX2MBOAT4 | |
| SCHEMBL20943404 | 0.95 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MAPK1EPHX2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3476832-B1 | CATIONIC LIPID | EISAI R&D MAN CO LTD (JP) | 2023-04-19 | — | — | EP | disclosed |
| EP-3733647-B1 | CATIONIC LIPID | EISAI R&D MAN CO LTD (JP) | 2022-06-15 | — | — | EP | disclosed |
| EP-3733647-B1 | CATIONIC LIPID | EISAI R&D MAN CO LTD (JP) | 2022-06-15 | — | — | EP | disclosed |
| US-10947193-B2 | Cationic lipid | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2021-03-16 | — | — | US | disclosed |
| US-10947193-B2 | Cationic lipid | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2021-03-16 | — | — | US | disclosed |
| EP-3733647-A1 | CATIONIC LIPID | Eisai R&D Management Co., Ltd. (JP) | 2020-11-04 | — | — | EP | disclosed |
| EP-3733647-A1 | CATIONIC LIPID | Eisai R&D Management Co., Ltd. (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-20200308111-A1 | Cationic Lipid | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-10-01 | — | — | US | disclosed |
| US-20200308111-A1 | Cationic Lipid | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-10-01 | — | — | US | disclosed |
| US-20190218180-A1 | Cationic Lipid | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2019-07-18 | — | — | US | disclosed |
| US-20190218180-A1 | Cationic Lipid | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2019-07-18 | — | — | US | disclosed |
| EP-3476832-A1 | CATIONIC LIPID | Eisai R&D Management Co., Ltd. (JP) | 2019-05-01 | — | — | EP | disclosed |
| EP-3476832-A1 | CATIONIC LIPID | Eisai R&D Management Co., Ltd. (JP) | 2019-05-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308111-A1 | Cationic Lipid | NPC1L1, NPC1, LPCAT1 | ALDH1A1 1890/4885L3MBTL1 146/4885MAPK1 1456/4885 |
| US-20190218180-A1 | Cationic Lipid | NPC1L1, NPC1, LPCAT1 | ALDH1A1 1462/4885L3MBTL1 344/4885MAPK1 1519/4885 |
| US-10947193-B2 | Cationic lipid | NPC1L1, NPC1, LPCAT1 | ALDH1A1 1890/4885L3MBTL1 146/4885MAPK1 1456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.