Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 18/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28592261 | 0.85 | MAPT (0.49) | NR1H2NR1I2MAPT | |
| SCHEMBL4611336 | 0.81 | NR1H2 (0.52) | NR1H2NR1I2 | |
| SCHEMBL28596673 | 0.80 | NR1H2 (0.51) | NR1H2NR1I2 | |
| SCHEMBL17974909 | 0.78 | NR1H2 (0.44) | NR1H2NR1I2 | |
| SCHEMBL4612085 | 0.78 | NR1H2 (0.46) | NR1H2NR1I2 | |
| SCHEMBL4611486 | 0.78 | NR1H2 (0.57) | NR1H2NR1I2 | |
| SCHEMBL28599366 | 0.78 | NR1H2 (0.49) | NR1H2NR1I2MAPT | |
| SCHEMBL19745708 | 0.78 | NR1H2 (0.40) | NR1H2NR1I2 | |
| SCHEMBL28592264 | 0.77 | NR1H2 (0.53) | NR1H2NR1I2 | |
| SCHEMBL30415546 | 0.77 | NR1H2 (0.53) | NR1H2NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190127397-A1 | Complexes for Nucleophilic, Radical, and Electrophilic Polyfluoroalkylation | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2019-05-02 | — | — | US | disclosed |
| US-20190127397-A1 | Complexes for Nucleophilic, Radical, and Electrophilic Polyfluoroalkylation | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127397-A1 | Complexes for Nucleophilic, Radical, and Electrophilic Polyfluoroalkylation | NBAS, PFAS, PCBP1 | NR1H2 633/4885NR1I2 959/4885MAPT 4687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.