Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 3/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGAV | P06756 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.44 |
| ▸ | GNPAT | O15228 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.42 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.42 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.42 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.42 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.42 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.42 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20950858 | 1.00 | ITGB1 (0.45) | ITGB1ITGA4ITGB3ITGAVITGA2B | |
| SCHEMBL20951507 | 0.86 | CTSS (0.46) | ITGB3ITGA2BGNPATCTSSCTSK | |
| SCHEMBL20951504 | 0.86 | CTSS (0.46) | ITGB3ITGA2BGNPATCTSSCTSK | |
| SCHEMBL20951916 | 0.85 | GAA (0.41) | ITGB3ITGAVITGA2BMEN1KMT2A | |
| SCHEMBL20951915 | 0.85 | GAA (0.41) | ITGB3ITGAVITGA2BMEN1KMT2A | |
| SCHEMBL20950960 | 0.85 | GRIA1 (0.45) | ITGB1ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL20952207 | 0.85 | GNPAT (0.44) | ITGB3ITGA2BGNPATCTSSCTSK | |
| SCHEMBL20952208 | 0.85 | GNPAT (0.44) | ITGB3ITGA2BGNPATCTSSCTSK | |
| SCHEMBL20950958 | 0.85 | GRIA1 (0.45) | ITGB1ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL20965495 | 0.73 | CA1 (0.39) | GNPATCTSSCTSKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11046729-B2 | Dipeptide analogs as TGF-beta inhibitors | SOUTHERN RESEARCH INSTITUTE (US) | 2021-06-29 | — | — | US | disclosed |
| US-20190127420-A1 | DIPEPTIDE ANALOGS AS TGF-BETA INHIBITORS | UAB RESEARCH FOUNDATION | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127420-A1 | DIPEPTIDE ANALOGS AS TGF-BETA INHIBITORS | TGFB1, TGFB2, SMAD3 | ITGB1 802/4885ITGA4 1672/4885ITGB3 526/4885 |
| US-11046729-B2 | Dipeptide analogs as TGF-beta inhibitors | TGFB1, TGFB2, SMAD3 | ITGB1 802/4885ITGA4 1672/4885ITGB3 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.