Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 19/20 | 0.70 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20952904 | 0.88 | RBP4 (0.74) | RBP4 | |
| SCHEMBL29598456 | 0.88 | RBP4 (0.74) | RBP4 | |
| SCHEMBL20695693 | 0.87 | RBP4 (0.73) | RBP4 | |
| SCHEMBL16118460 | 0.87 | RBP4 (0.73) | RBP4SCD5 | |
| SCHEMBL29598209 | 0.87 | RBP4 (0.73) | RBP4 | |
| SCHEMBL29597131 | 0.87 | RBP4 (0.73) | RBP4SCD5 | |
| SCHEMBL29597749 | 0.84 | RBP4 (0.69) | RBP4 | |
| SCHEMBL26315207 | 0.84 | RBP4 (0.69) | RBP4 | |
| SCHEMBL17505322 | 0.84 | RBP4 (0.69) | RBP4 | |
| SCHEMBL26315214 | 0.84 | RBP4 (0.68) | RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10273243-B2 | 4-phenylpiperidines, their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10273243-B2 | 4-phenylpiperidines, their preparation and use | HTR3C, HRH4, CYP4F3 | RBP4 2619/4885SCD5 4292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.