SCHEMBL20953417

SCHEMBL20953417

Nc1ccn(C2OC(CO)C(O)C(O)C2O)c(=S)n1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.70
MTOR P42345 2/20 0.70
THRB P10828 1/20 0.70
MDM2 Q00987 1/20 0.70
NCOA1 Q15788 1/20 0.70
NCOA3 Q9Y6Q9 1/20 0.70
ALDH1A1 P00352 2/20 0.50
TP53 P04637 2/20 0.50
GMNN O75496 1/20 0.50
NFKB1 P19838 1/20 0.50
DNMT1 P26358 1/20 0.50
THPO P40225 1/20 0.50
HTT P42858 1/20 0.50
RAB9A P51151 1/20 0.50
BLM P54132 1/20 0.50
HBB P68871 1/20 0.50
PMP22 Q01453 1/20 0.50
SLC29A1 Q99808 3/20 0.49
SLC28A1 O00337 2/20 0.49
SLC28A2 O43868 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16946221 1.00 LMNA (0.70) LMNAMTORTHRBMDM2NCOA1
SCHEMBL16941689 1.00 LMNA (0.70) LMNAMTORTHRBMDM2NCOA1
SCHEMBL20953418 1.00 LMNA (0.70) LMNAMTORTHRBMDM2NCOA1
SCHEMBL30664789 0.99 LMNA (0.72) LMNAMTORTHRBMDM2NCOA1
SCHEMBL288517 0.99 LMNA (0.72) LMNAMTORTHRBMDM2NCOA1
SCHEMBL6302404 0.99 LMNA (0.72) LMNAMTORTHRBMDM2NCOA1
SCHEMBL42103 0.99 LMNA (0.72) LMNAMTORTHRBMDM2NCOA1
Water SCHEMBL6475042 0.97 LMNA (0.70) LMNAMTORTHRBMDM2NCOA1
Water SCHEMBL6475036 0.97 LMNA (0.70) LMNAMTORTHRBMDM2NCOA1
SCHEMBL21418700 0.87 LMNA (0.57) LMNAMTORTHRBMDM2NCOA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10273313-B2 Multimeric mannosides, a process for preparing the same and their uses as a drug CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2019-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10273313-B2 Multimeric mannosides, a process for preparing the same and their uses as a drug MANBA, MAN2A1, MAN2B2 LMNA 1947/4885MTOR 2959/4885THRB 4791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.