SCHEMBL42103

SCHEMBL42103

Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=S)n1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.72
MTOR P42345 2/20 0.72
THRB P10828 1/20 0.72
MDM2 Q00987 1/20 0.72
NCOA1 Q15788 1/20 0.72
NCOA3 Q9Y6Q9 1/20 0.72
ALDH1A1 P00352 2/20 0.51
TP53 P04637 2/20 0.51
GMNN O75496 1/20 0.51
NFKB1 P19838 1/20 0.51
DNMT1 P26358 1/20 0.51
THPO P40225 1/20 0.51
HTT P42858 1/20 0.51
RAB9A P51151 1/20 0.51
BLM P54132 1/20 0.51
HBB P68871 1/20 0.51
PMP22 Q01453 1/20 0.51
SLC29A1 Q99808 3/20 0.50
SLC28A1 O00337 2/20 0.50
SLC28A2 O43868 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6302404 1.00 LMNA (0.72) LMNAMTORTHRBMDM2NCOA1
SCHEMBL288517 1.00 LMNA (0.72) LMNAMTORTHRBMDM2NCOA1
SCHEMBL30664789 1.00 LMNA (0.72) LMNAMTORTHRBMDM2NCOA1
SCHEMBL16941689 0.99 LMNA (0.70) LMNAMTORTHRBMDM2NCOA1
SCHEMBL16946221 0.99 LMNA (0.70) LMNAMTORTHRBMDM2NCOA1
Water SCHEMBL6475036 0.99 LMNA (0.70) LMNAMTORTHRBMDM2NCOA1
Water SCHEMBL6475042 0.99 LMNA (0.70) LMNAMTORTHRBMDM2NCOA1
SCHEMBL20953417 0.99 LMNA (0.70) LMNAMTORTHRBMDM2NCOA1
SCHEMBL20953418 0.99 LMNA (0.70) LMNAMTORTHRBMDM2NCOA1
SCHEMBL16576161 0.88 LMNA (0.57) LMNAMTORTHRBMDM2NCOA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14254 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139030-A1 CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION SHATTUCK LABS INC (US) 2026-05-21 US claimed
EP-4740010-A1 NEGATIVE TUNE STANDARD FOR MASS SPECTROMETRY Agilent Technologies, Inc. (US) 2026-05-13 EP claimed
EP-4720279-A2 CIS-REGULATORY ELEMENTS OF TRANSLATION AND METHODS USING SAME Yale University (US) 2026-04-08 EP claimed
EP-4716748-A2 METHOD OF MODULATING MRNA TRANSLATION Yale University (US) 2026-04-01 EP claimed
EP-4711452-A2 KLOTHO MRNA ADvantage Therapeutics, Inc. (US) 2026-03-18 EP claimed
US-12577554-B2 Methods for purification of messenger RNA TRANSLATE BIO, INC. (US) 2026-03-17 US claimed
EP-4705468-A1 MAMMALIAN POLYCISTRONIC EXPRESSION SYSTEM FOR DIRECT TRANSLATION FROM RNA AND SECRETION OF CARGO California Institute of Technology (US) 2026-03-11 EP claimed
EP-4705481-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2026-03-11 EP claimed
US-12569572-B2 Messenger RNA therapy for the treatment of Friedreich's ataxia TRANSLATE BIO, INC. (US) 2026-03-10 US claimed
US-20260049338-A1 METHODS AND PRODUCTS FOR TRANSFECTING CELLS FACTOR BIOSCIENCE INC (US) 2026-02-19 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0673783-B1 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORP (US) 2000-07-05 EP claimed
CN-1231895-A Use of 2',3'-dideoxy-3'-thiocytidine in medicine for treatment of hepatitis B JIANG WEI (CN) 1999-10-20 CN claimed
EP-0795029-A1 CHEMICAL LABELLING OF OBJECTS Pabio (NO) 1997-09-17 EP claimed
US-5659348-A APPLYING TO A SUBSTRATE XEROX CORPORATION (US) 1997-08-19 US claimed
WO-1996017954-A1 CHEMICAL LABELLING OF OBJECTS PABIO (DK) 1996-06-13 WO claimed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
WO-1991004982-A1 FURTHER ANTIVIRAL PYRIMIDINE NUCLEOSIDES UNIVERSITY OF BIRMINGHAM (GB) 1991-04-18 WO claimed
EP-0421777-A1 Further antiviral pyrimidine nucleosides THE UNIVERSITY OF BIRMINGHAM (GB) 1991-04-10 EP claimed