Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.73 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.73 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.73 |
| ▸ | PDE5A | O76074 | 1/20 | 0.69 |
| ▸ | ESR1 | P03372 | 1/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.69 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.69 |
| ▸ | AKT1 | P31749 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.59 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | GABRP | O00591 | 1/20 | 0.51 |
| ▸ | GABRD | O14764 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2688888 | 0.92 | PDE5A (0.82) | DYRK1ADYRK1BABCB1PDE5AESR1 | |
| SCHEMBL20954090 | 0.90 | PDE5A (0.83) | DYRK1ADYRK1BABCB1PDE5AESR1 | |
| SCHEMBL20954093 | 0.85 | ABCG2 (0.82) | DYRK1ADYRK1BABCB1AKT1ABCG2 | |
| SCHEMBL20045165 | 0.85 | DYRK1A (1.00) | DYRK1ADYRK1BABCB1PDE5AESR1 | |
| SCHEMBL1231403 | 0.82 | PDE4D (1.00) | DYRK1ADYRK1BABCB1PDE5AESR1 | |
| SCHEMBL29808504 | 0.82 | PDE4D (1.00) | DYRK1ADYRK1BABCB1PDE5AESR1 | |
| SCHEMBL3192507 | 0.80 | PDE5A (0.83) | DYRK1ADYRK1BABCB1PDE5AESR1 | |
| SCHEMBL4828372 | 0.78 | AKT1 (1.00) | DYRK1ADYRK1BPDE5AESR1PDE4D | |
| SCHEMBL4227433 | 0.78 | PDE5A (0.80) | DYRK1ADYRK1BPDE5AESR1PDE4D | |
| SCHEMBL3336171 | 0.77 | ALOX5 (0.77) | DYRK1ADYRK1BABCB1PDE5AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12474327-B2 | Metabolic profiling for the diagnosis of a subset of idiopathic autism spectrum disorder patients, ADS Phenotype 1 | STALICLA SA (CH) | 2025-11-18 | — | — | US | disclosed |
| US-20220003753-A1 | METABOLIC PROFILING FOR THE DIAGNOSIS OF A SUBSET OF IDIOPATHIC AUTISM SPECTRUM DISORDER PATIENTS, ADS PHENOTYPE 1 | STALICLA SA (CH) | 2022-01-06 | — | — | US | disclosed |
| EP-3877540-A1 | METABOLIC PROFILING FOR THE DIAGNOSIS OF A SUBSET OF IDIOPATHIC AUTISM SPECTRUM DISORDER PATIENTS, ASD PHENOTYPE 1 | Stalicla S.A. (CH) | 2021-09-15 | — | — | EP | disclosed |
| CN-113166811-A | Metabolic profiling for diagnosing subtype ASD phenotype 1 in patients with idiopathic autism spectrum disorders | 斯大利卡拉公司 | 2021-07-23 | — | — | CN | disclosed |
| US-20210187127-A1 | CHALLENGE TEST FOR DIAGNOSING A SUBTYPE OF AUTISM SPECTRUM DISEASE | STALICLA SA (CH) | 2021-06-24 | — | — | US | disclosed |
| EP-3706806-A1 | CHALLENGE TEST FOR DIAGNOSING A SUBTYPE OF AUTISM SPECTRUM DISEASE | Stalicla S.A. (CH) | 2020-09-16 | — | — | EP | disclosed |
| US-20190134229-A1 | METHOD OF IDENTIFYING ASD PHENOTYPE 1 PATIENTS | Stalicla S.A. (CH) | 2019-05-09 | — | — | US | disclosed |
| US-20190134230-A1 | CHALLENGE TEST FOR DIAGNOSING SUBTYPES OF ASD | Stalicla S.A. (CH) | 2019-05-09 | — | — | US | disclosed |
| EP-3479845-A1 | CHALLENGE TEST FOR DIAGNOSING SUBTYPE OF AUTISM SPECTRUM DISEASE | Stalicla S.A. (CH) | 2019-05-08 | — | — | EP | disclosed |