Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CTH | P32929 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GNPAT | O15228 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL28463137 | 0.91 | GLRA1 (0.48) | CA2CA4GABRR1LMNATDP1 | |
| Hydroxyamine SCHEMBL631500 | 0.90 | CA2 (0.45) | CA2CA4GABRR1LMNATDP1 | |
| SCHEMBL1457564 | 0.90 | CA2 (0.48) | CA2CA4TDP1FOLH1TGFBR1 | |
| SCHEMBL22019 | 0.90 | CA2 (0.48) | CA2CA4TDP1FOLH1TGFBR1 | |
| SCHEMBL2916092 | 0.90 | CA2 (0.48) | CA2CA4TDP1FOLH1TGFBR1 | |
| SCHEMBL2910640 | 0.90 | CA2 (0.48) | CA2CA4TDP1FOLH1TGFBR1 | |
| SCHEMBL18419474 | 0.87 | CA2 (0.47) | CA2CA4TDP1FOLH1TGFBR1 | |
| SCHEMBL1419353 | 0.87 | CA2 (0.47) | CA2CA4TDP1FOLH1TGFBR1 | |
| SCHEMBL5327417 | 0.87 | CA2 (0.47) | CA2CA4TDP1FOLH1TGFBR1 | |
| SCHEMBL3055923 | 0.87 | CA2 (0.47) | CA2CA4TDP1FOLH1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3480287-B1 | SOLID WATER-SOLUBLE CLEANING COMPOSITION | DALLI WERKE GMBH & CO KG (DE) | 2020-03-18 | — | — | EP | claimed |
| EP-3480287-A1 | SOLID WATER-SOLUBLE CLEANING COMPOSITION | Dalli-Werke GmbH & Co. KG (DE) | 2019-05-08 | — | — | EP | claimed |
| EP-3480287-B1 | SOLID WATER-SOLUBLE CLEANING COMPOSITION | DALLI WERKE GMBH & CO KG (DE) | 2020-03-18 | — | — | EP | disclosed |
| EP-3480287-A1 | SOLID WATER-SOLUBLE CLEANING COMPOSITION | Dalli-Werke GmbH & Co. KG (DE) | 2019-05-08 | — | — | EP | disclosed |