Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22270961 | 0.75 | KDM4E (0.39) | KMT2AKDM4EMEN1NPC1HSP90AA1 | |
| SCHEMBL23349947 | 0.74 | TRIM24 (0.44) | CYP2A6KMT2AKDM4EMEN1NPC1 | |
| SCHEMBL27413953 | 0.73 | CCR1 (0.53) | CYP2A6KMT2AKDM4EMEN1NPC1 | |
| SCHEMBL30935945 | 0.73 | CCR1 (0.53) | CYP2A6KMT2AKDM4EMEN1NPC1 | |
| SCHEMBL20954574 | 0.73 | KDM4E (0.36) | KMT2AKDM4EMEN1NPC1RAB9A | |
| SCHEMBL2176528 | 0.72 | AXL (0.42) | KMT2AKDM4EMEN1NPC1HSP90AA1 | |
| SCHEMBL30489898 | 0.72 | AXL (0.42) | KMT2AKDM4EMEN1NPC1HSP90AA1 | |
| SCHEMBL26425877 | 0.72 | TTR (0.52) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2713045 | 0.71 | HSP90AA1 (0.42) | KMT2AKDM4EMEN1HSP90AA1IDO1 | |
| SCHEMBL3971484 | 0.71 | KDM4E (0.40) | KMT2AKDM4EMEN1HSP90AA1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101747339-A | 1'-thio-aza indirubin compound, application and preparation method thereof | UNIV SHANGHAI JIAOTONG | 2010-06-23 | — | — | CN | claimed |
| CN-1489579-A | 7-heterocyclyl quinoline and thieno [2, 3-b ] pyridine derivatives as gonadotropin-releasing hormone antagonists | ����-������ҩƷ��˾ | 2004-04-14 | — | — | CN | claimed |
| CN-111491935-B | Novel analogs as modulators of androgen and glucocorticoid receptors | 昂科斯特拉公司 | 2023-08-22 | — | — | CN | disclosed |
| EP-3707143-B9 | NEW ANALOGS AS ANDROGEN RECEPTOR AND GLUCOCORTICOID RECEPTOR MODULATORS | ONCOSTELLAE S L (ES) | 2023-04-12 | — | — | EP | disclosed |
| EP-3707143-B1 | NEW ANALOGS AS ANDROGEN RECEPTOR AND GLUCOCORTICOID RECEPTOR MODULATORS | ONCOSTELLAE S L (ES) | 2022-12-28 | — | — | EP | disclosed |
| US-11453660-B2 | Androgen receptor and glucocorticoid receptor modulators | ONCOSTELLAE, S.L. | 2022-09-27 | — | — | US | disclosed |
| US-20200325123-A1 | NEW ANALOGS AS ANDROGEN RECEPTOR AND GLUCOCORTICOID RECEPTOR MODULATORS | ONCOSTELLAE, S.L. (ES) | 2020-10-15 | — | — | US | disclosed |
| EP-3707143-A1 | NEW ANALOGS AS ANDROGEN RECEPTOR AND GLUCOCORTICOID RECEPTOR MODULATORS | Oncostellae, S.L. (ES) | 2020-09-16 | — | — | EP | disclosed |
| EP-3480201-A1 | NEW ANALOGS AS ANDROGEN RECEPTOR AND GLUCOCORTICOID RECEPTOR MODULATORS | Oncostellae, S.L. (ES) | 2019-05-08 | — | — | EP | disclosed |
| CN-101747339-B | 1' -thiazaindirubin compound, application and preparation method thereof | UNIV SHANGHAI JIAOTONG | 2012-04-25 | — | — | CN | disclosed |
| CN-101747339-B | 1' -thiazaindirubin compound, application and preparation method thereof | UNIV SHANGHAI JIAOTONG | 2012-04-25 | — | — | CN | disclosed |
| CN-101747339-A | 1'-thio-aza indirubin compound, application and preparation method thereof | UNIV SHANGHAI JIAOTONG | 2010-06-23 | — | — | CN | disclosed |
| CN-101747339-A | 1'-thio-aza indirubin compound, application and preparation method thereof | UNIV SHANGHAI JIAOTONG | 2010-06-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200325123-A1 | NEW ANALOGS AS ANDROGEN RECEPTOR AND GLUCOCORTICOID RECEPTOR MODULATORS | NR5A1, AR, NR3C1 | CYP2A6 511/4885KMT2A 4588/4885KDM4E 3692/4885 |
| US-11453660-B2 | Androgen receptor and glucocorticoid receptor modulators | AR, NR5A1, NR3C1 | CYP2A6 445/4885KMT2A 4408/4885KDM4E 3611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.