SCHEMBL20955860

SCHEMBL20955860

CC(C)(C)P(C(=O)c1ccccc1)C(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.46
TSHR P16473 4/20 0.46
CES2 O00748 4/20 0.46
ALDH1A1 P00352 3/20 0.46
DAO P14920 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
TDP1 Q9NUW8 4/20 0.45
HSD17B10 Q99714 2/20 0.45
MAPK1 P28482 2/20 0.43
TRPA1 O75762 1/20 0.43
GSK3B P49841 1/20 0.43
HIF1A Q16665 1/20 0.43
POLB P06746 2/20 0.42
CYP3A4 P08684 2/20 0.42
MAPT P10636 2/20 0.42
PARP1 P09874 1/20 0.42
CYP2C19 P33261 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27510084 0.75 CES1 (0.50) CES1TSHRCES2ALDH1A1DAO
SCHEMBL1346680 0.74 CES1 (0.55) CES1TSHRCES2ALDH1A1DAO
SCHEMBL28143072 0.73 CES1 (0.48) CES1TSHRCES2ALDH1A1DAO
Benzoic Acid SCHEMBL7999427 0.72 TSHR (0.78) CES1TSHRCES2ALDH1A1DAO
SCHEMBL543379 0.72 CES1 (0.52) CES1TSHRCES2ALDH1A1DAO
SCHEMBL226691 0.70 CES1 (0.58) CES1TSHRCES2ALDH1A1DAO
SCHEMBL21109870 0.70 CES1 (0.58) CES1TSHRCES2ALDH1A1DAO
SCHEMBL4417015 0.70 CES1 (0.50) CES1TSHRCES2ALDH1A1DAO
SCHEMBL4618681 0.70 CES1 (0.58) CES1TSHRCES2ALDH1A1DAO
Benzophenone SCHEMBL28321860 0.70 ALDH1A1 (0.74) TSHRALDH1A1DAONAPRTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3480204-B1 ORGANIC MAGNESIUM PHOSPHIDE AND METHOD FOR PRODUCING SAME, ORGANIC MAGNESIUM PHOSPHIDE COMPLEX AND METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING ORGANIC PHOSPHORUS-CONTAINING COMPOUND USING SAID PHOSPHIDE HOKKO CHEM IND CO (JP) 2022-09-07 EP disclosed
CN-109476680-B Organic magnesium phosphide, process for producing the same, complex thereof, process for producing the same, and process for producing organic phosphorus compound using the same 北兴化学工业株式会社 2022-06-28 CN disclosed
US-20190248815-A1 ORGANIC MAGNESIUM PHOSPHIDE AND MANUFACTURING METHOD THEREOF, ORGANIC MAGNESIUM PHOSPHIDE COMPLEX AND MANUFACTURING METHOD THEREOF, AND MANUFACTURING METHOD OF ORGANIC PHOSPHORUS COMPOUND USING SAID PHOSPHIDE HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2019-08-15 US disclosed
EP-3480204-A1 ORGANIC MAGNESIUM PHOSPHIDE AND METHOD FOR PRODUCING SAME, ORGANIC MAGNESIUM PHOSPHIDE COMPLEX AND METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING ORGANIC PHOSPHORUS-CONTAINING COMPOUND USING SAID PHOSPHIDE Hokko Chemical Industry Co., Ltd. (JP) 2019-05-08 EP disclosed
CN-109476680-A The manufacturing method of organic magnesium phosphide and manufacturing method, its complex compound and manufacturing method and the organic phosphorus compound using the phosphide 北兴化学工业株式会社 2019-03-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190248815-A1 ORGANIC MAGNESIUM PHOSPHIDE AND MANUFACTURING METHOD THEREOF, ORGANIC MAGNESIUM PHOSPHIDE COMPLEX AND MANUFACTURING METHOD THEREOF, AND MANUFACTURING METHOD OF ORGANIC PHOSPHORUS COMPOUND USING SAID PHOSPHIDE IPMK, PPIP5K2, PIP4K2C CES1 2346/4885TSHR 254/4885CES2 3533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.