Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.40 |
| ▸ | CFD | P00746 | 4/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20956856 | 1.00 | HDAC1 (0.40) | HDAC1CFDITGA4ITGB1DPP4 | |
| SCHEMBL20956857 | 1.00 | HDAC1 (0.40) | HDAC1CFDITGA4ITGB1DPP4 | |
| SCHEMBL23119908 | 0.88 | HDAC1 (0.40) | HDAC1HDAC2HDAC3NCOR2HDAC8 | |
| SCHEMBL19540504 | 0.84 | HDAC2 (0.41) | HDAC1CFDITGA4ITGB1HDAC2 | |
| SCHEMBL20956735 | 0.82 | HCAR3 (0.40) | — | |
| SCHEMBL23119916 | 0.82 | HCAR3 (0.40) | — | |
| SCHEMBL29764647 | 0.81 | CFD (0.36) | HDAC1CFDITGA4ITGB1HDAC2 | |
| SCHEMBL20956773 | 0.80 | CHRM3 (0.41) | HDAC1DPP4DPP8DPP9DPP7 | |
| SCHEMBL20956776 | 0.80 | CHRM3 (0.41) | HDAC1DPP4DPP8DPP9DPP7 | |
| SCHEMBL20956778 | 0.78 | HDAC1 (0.39) | HDAC1HDAC2HDAC3NCOR2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190135794-A1 | BENZIMIDAZOLE-LINKED INDOLE COMPOUND ACTING AS NOVEL DIVALENT IAP ANTAGONIST | MEDSHINE DISCOVERY INC. (CN) | 2019-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190135794-A1 | BENZIMIDAZOLE-LINKED INDOLE COMPOUND ACTING AS NOVEL DIVALENT IAP ANTAGONIST | BIRC2, BIRC5, BIRC8 | HDAC1 444/4885CFD 4820/4885ITGA4 4628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.