Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR known ✓ | P00533 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL31483849 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| Pyridine SCHEMBL7656088 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| Pyridine SCHEMBL3261023 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| Pyridine SCHEMBL6427981 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| Pyridine SCHEMBL2126952 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| Pyridine SCHEMBL5968326 | 0.98 | ALDH1A1 (0.57) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| Pyridine SCHEMBL28538739 | 0.98 | ALDH1A1 (0.57) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| Pyridine SCHEMBL28981792 | 0.98 | ALDH1A1 (0.57) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| Pyridine SCHEMBL28227884 | 0.98 | ALDH1A1 (0.57) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| Pyridine SCHEMBL28166378 | 0.98 | ALDH1A1 (0.57) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 28844 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121873631-B | Spin-on carbon composition, semiconductor preparation method and semiconductor device | Jiageng Innovation Laboratory (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122080081-A | Photochromic Pt (II) complex and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-116813686-B | Asymmetric synthesis method and application of 7-oxo-resorcinol lactone | 欣凯医药化工中间体（上海）有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122011678-A | Preparation method of LED lamp bead rubber sleeve | 吉安华翌电子有限公司 | 2026-05-12 | — | — | CN | claimed |
| EP-3940747-B1 | NOVEL ETCHING PATTERN FORMING METHOD IN SEMICONDUCTOR MANUFACTURING PROCESS | YOUNG CHANG CHEMICAL CO LTD (KR) | 2026-05-06 | — | — | EP | claimed |
| EP-4735459-A1 | METHODS AND INTERMEDIATES FOR PREPARING ANTIVIRAL PRODRUGS | GILEAD SCIENCES, INC. (US) | 2026-05-06 | — | — | EP | claimed |
| US-20260062421-A1 | NOVEL PROCESSES FOR PREPARING CAMPTOTHECIN DERIVATIVES | IMMUNOGEN INC (US) | 2026-03-05 | — | — | US | claimed |
| EP-4688726-A1 | PROCESS FOR THE PREPARATION OF AMINE INTERMEDIATES | Adama Agan Ltd. (IL) | 2026-02-11 | — | — | EP | claimed |
| EP-4688911-A1 | MACRO-CYCLIC POLYESTER OLIGOMERS PRODUCED DIRECTLY FROM DIOLS AND AROMATIC DICARBOXYLIC ACIDS, AND RELATED METHODS | JM Mihalich LLC (US) | 2026-02-11 | — | — | EP | claimed |
| US-12535736-B2 | Anti-reflective hard mask composition | CHEMPOLE CO., LTD. (KR) | 2026-01-27 | — | — | US | claimed |
| WO-1987005028-A1 | ANTI-INFLAMMATORY CARBOXY PREGNANE DERIVATIVES | FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY (US) | 1987-08-27 | — | — | WO | claimed |
| EP-0073061-B1 | OPTICALLY UNIFORM BETA-LACTAMS, THEIR PREPARATION AND USE IN THE PREPARATION OF ANTIMICROBIAL BETA-LACTAMS, AND STARTING COMPOUNDS FOR USE IN THEIR PREPARATION | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-03-04 | — | — | EP | claimed |
| US-4611065-A | Method for preparing 5-fluoroprostacyclins | G. D. SEARLE & CO. (US) | 1986-09-09 | — | — | US | claimed |
| EP-0190620-A1 | Method for 5-fluoroprostacyclins | G.D. Searle & Co., Ltd. (US) | 1986-08-13 | — | — | EP | claimed |
| EP-0160842-A2 | 2-Substituted ergoline derivatives, processes for their preparation, and their use as medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-11-13 | — | — | EP | claimed |
| EP-0033536-B1 | 6(R)-(2-(8'-ETHERIFIED-HYDROXY-2',6'-DIMETHYLPOLYHYDRO-NAPHTHYL-1')-ETHYL)-4(R)-HYDROXY-3,4,5,6-TETRAHYDRO-2H-PYRAN-2-ONES, THE HYDROXY ACID FORM OF SAID PYRANONES, THE SALTS OF SAID ACID FORM, PROCESS FOR PREPARING THE SAME AND AN ANTIHYPERCHOLESTEROLEMIC PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | MERCK & CO. INC. (US) | 1984-09-12 | — | — | EP | claimed |
| US-4395561-A | Synthesis of 3-hydroxyoxetane | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1983-07-26 | — | — | US | claimed |
| EP-0033536-A2 | 6(R)-(2-(8'-etherified-hydroxy-2',6'-dimethylpolyhydro-naphthyl-1')-ethyl)-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-ones, the hydroxy acid form of said pyranones, the salts of said acid form, process for preparing the same and an antihypercholesterolemic pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1981-08-12 | — | — | EP | claimed |
| US-4102193-A | EPOXY RESIN CARRIER | WESTINGHOUSE ELECTRIC CORP. (US) | 1978-07-25 | — | — | US | claimed |
| US-4046733-A | ROOM TEMPERATURE CURABLE RESIN | WESTINGHOUSE ELECTRIC CORPORATION (US) | 1977-09-06 | — | — | US | claimed |