SCHEMBL20959986

SCHEMBL20959986

[N-]=[N+]=NC12O[C@@H](c3ccc4c(N)nc(F)nn34)[C@H](F)[C@@]1(O)C2O

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ POLRMT O00411 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19778892 1.00 POLRMT (0.34) POLRMT
SCHEMBL19779094 0.90 POLRMT (0.32) POLRMT
SCHEMBL20960069 0.81 — —
SCHEMBL20756115 0.77 POLRMT (0.41) POLRMT
SCHEMBL16698792 0.77 POLRMT (0.41) POLRMT
SCHEMBL19779072 0.74 POLRMT (0.51) POLRMT
SCHEMBL20756525 0.73 POLRMT (0.34) POLRMT
SCHEMBL19962800 0.73 — —
SCHEMBL20642796 0.73 — —
SCHEMBL19779079 0.72 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3068405-B1 PYRROLO [1,2,F][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS GILEAD SCIENCES INC (US) 2019-05-01 — — EP disclosed
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