Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 5/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22096275 | 0.79 | RIPK1 (0.32) | RIPK1ACVRL1 | |
| SCHEMBL21283655 | 0.75 | RIPK1 (0.35) | RIPK1ACVRL1 | |
| SCHEMBL12392887 | 0.70 | RET (0.41) | RIPK1ACVRL1 | |
| SCHEMBL5141048 | 0.70 | RIPK1 (0.40) | RIPK1ACVRL1 | |
| SCHEMBL22096280 | 0.70 | RIPK1 (0.33) | RIPK1ACVRL1 | |
| SCHEMBL24239192 | 0.69 | MAP4K4 (0.40) | RIPK1ACVRL1 | |
| SCHEMBL26825490 | 0.68 | MAP4K4 (0.39) | RIPK1ACVRL1 | |
| SCHEMBL25013926 | 0.68 | RIPK1 (0.41) | RIPK1ACVRL1 | |
| SCHEMBL26381654 | 0.68 | RIPK1 (0.41) | RIPK1ACVRL1 | |
| SCHEMBL18214622 | 0.68 | ACVRL1 (0.34) | RIPK1ACVRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068405-B1 | PYRROLO [1,2,F][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES INC (US) | 2019-05-01 | — | — | EP | disclosed |