SCHEMBL20960591

SCHEMBL20960591

SC1CCCc2c1[nH]c1ccccc21

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BRD3 Q15059 1/20 0.67
RB1 P06400 7/20 0.58
SIRT1 Q96EB6 2/20 0.58
SIRT2 Q8IXJ6 1/20 0.58
ADRA1D P25100 1/20 0.51
ADRA1A P35348 1/20 0.51
ADRA1B P35368 1/20 0.51
HTR7 P34969 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C19 P33261 1/20 0.49
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MAPKAPK2 P49137 1/20 0.46
CHRNA7 P36544 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1877922 0.80 BRD3 (0.67) BRD3RB1SIRT1SIRT2ADRA1D
SCHEMBL29625801 0.80 BRD3 (0.67) BRD3RB1SIRT1SIRT2ADRA1D
SCHEMBL7088610 0.80 BRD3 (0.67) BRD3RB1SIRT1SIRT2ADRA1D
SCHEMBL1871473 0.80 BRD3 (0.67) BRD3RB1SIRT1SIRT2ADRA1D
SCHEMBL10924730 0.80 BRD3 (1.00) BRD3RB1SIRT1SIRT2ADRA1D
SCHEMBL9665012 0.79 BRD3 (0.65) BRD3RB1SIRT1SIRT2ADRA1D
SCHEMBL9610870 0.79 BRD3 (0.65) BRD3RB1SIRT1SIRT2ADRA1D
SCHEMBL9610867 0.79 BRD3 (0.65) BRD3RB1SIRT1SIRT2ADRA1D
Hydrochloric Acid SCHEMBL4023634 0.79 BRD3 (0.65) BRD3RB1SIRT1SIRT2ADRA1D
Hydrochloric Acid SCHEMBL28459560 0.79 BRD3 (0.65) BRD3RB1SIRT1SIRT2ADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2650274-B1 A thionation process and a thionating agent VIRONOVA THIONATION AB (SE) 2019-05-01 EP disclosed