Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD3 | Q15059 | 1/20 | 0.67 |
| ▸ | RB1 | P06400 | 7/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.58 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1871473 | 0.80 | BRD3 (0.67) | BRD3RB1SIRT1SIRT2ADRA1D | |
| SCHEMBL7088610 | 0.80 | BRD3 (0.67) | BRD3RB1SIRT1SIRT2ADRA1D | |
| SCHEMBL20960591 | 0.80 | BRD3 (0.67) | BRD3RB1SIRT1SIRT2ADRA1D | |
| SCHEMBL10924730 | 0.80 | BRD3 (1.00) | BRD3RB1SIRT1SIRT2ADRA1D | |
| SCHEMBL29625801 | 0.80 | BRD3 (0.67) | BRD3RB1SIRT1SIRT2ADRA1D | |
| SCHEMBL9665012 | 0.79 | BRD3 (0.65) | BRD3RB1SIRT1SIRT2ADRA1D | |
| SCHEMBL9610867 | 0.79 | BRD3 (0.65) | BRD3RB1SIRT1SIRT2ADRA1D | |
| SCHEMBL9610870 | 0.79 | BRD3 (0.65) | BRD3RB1SIRT1SIRT2ADRA1D | |
| Hydrochloric Acid SCHEMBL4023634 | 0.79 | BRD3 (0.65) | BRD3RB1SIRT1SIRT2ADRA1D | |
| Methane SCHEMBL28731797 | 0.79 | BRD3 (0.65) | BRD3RB1SIRT1SIRT2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107235891-A | A kind of preparation method of 4 bromine carbazole | 北京八亿时空液晶科技股份有限公司 | 2017-10-10 | — | — | CN | claimed |
| CN-107235891-A | A kind of preparation method of 4 bromine carbazole | 北京八亿时空液晶科技股份有限公司 | 2017-10-10 | — | — | CN | disclosed |
| US-7935722-B2 | Tetrahydrocarbazole derivatives useful as androgen receptor modulators | ELI LILLY AND COMPANY (US) | 2011-05-03 | — | — | US | disclosed |
| EP-1902026-B1 | TETRAHYDROCARBAZOLE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS (SARM) | LILLY CO ELI (US) | 2010-02-17 | — | — | EP | disclosed |
| US-20100022550-A1 | TETRAHYDROCARBAZOLE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS | CELLECTIS (FR) | 2010-01-28 | — | — | US | disclosed |
| EP-1902026-A2 | TETRAHYDROCARBAZOLE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS (SARM) | ELI LILLY AND COMPANY (US) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007002181-A2 | TETRAHYDROCARBAZOLE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS (SARM) | ELI LILLY AND COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022550-A1 | TETRAHYDROCARBAZOLE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS | AR, SHBG, CYP17A1 | BRD3 1879/4885RB1 3354/4885SIRT1 894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.