Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 7/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 3/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13065475 | 0.86 | S1PR4 (0.35) | S1PR3LMNASMN1; SMN2HSD17B10EGFR | |
| SCHEMBL20961969 | 0.76 | S1PR3 (0.39) | S1PR3S1PR1EGFRS1PR4S1PR2 | |
| SCHEMBL15950870 | 0.75 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2HSD17B10EGFRRPS6KB1 | |
| SCHEMBL2623141 | 0.73 | LMNA (0.64) | LMNASMN1; SMN2HSD17B10EGFRRPS6KB1 | |
| SCHEMBL14713436 | 0.73 | LMNA (0.64) | LMNASMN1; SMN2HSD17B10EGFRRPS6KB1 | |
| SCHEMBL5019518 | 0.73 | LMNA (0.64) | LMNASMN1; SMN2HSD17B10EGFRRPS6KB1 | |
| SCHEMBL7781146 | 0.72 | RPS6KB1 (0.49) | LMNASMN1; SMN2HSD17B10EGFRRPS6KB1 | |
| SCHEMBL7773690 | 0.72 | LMNA (0.43) | LMNASMN1; SMN2HSD17B10EGFRRPS6KB1 | |
| SCHEMBL11900473 | 0.71 | ALPL (0.42) | LMNASMN1; SMN2HSD17B10EGFRPIK3CG | |
| SCHEMBL4569248 | 0.70 | LMNA (0.44) | LMNASMN1; SMN2HSD17B10EGFRRPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427195-B1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INTELLIKINE LLC (US) | 2019-05-01 | — | — | EP | disclosed |