Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.47 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24179835 | 0.92 | PRSS1 (0.55) | PRSS1PRSS2PRSS3GRIN1GRIN2A | |
| SCHEMBL24179827 | 0.90 | PRSS1 (0.58) | PRSS1PRSS2PRSS3GRIN1GRIN2A | |
| SCHEMBL20964423 | 0.90 | PRSS1 (0.61) | PRSS1PRSS2PRSS3GRIN1GRIN2A | |
| SCHEMBL24179818 | 0.89 | PRSS1 (0.51) | PRSS1PRSS2PRSS3GRIN1GRIN2A | |
| SCHEMBL20964417 | 0.87 | TLR2 (0.59) | PRSS1PRSS2PRSS3GRIN1GRIN2A | |
| SCHEMBL20964497 | 0.87 | CALCRL (0.58) | GRIA1CTSLF2ITGB3ITGA2B | |
| SCHEMBL20964428 | 0.86 | GRIN1 (0.58) | PRSS1PRSS2PRSS3GRIN1GRIN2A | |
| SCHEMBL20964419 | 0.86 | PRSS1 (0.56) | PRSS1PRSS2PRSS3GRIN1GRIN2A | |
| SCHEMBL20964471 | 0.86 | PRSS1 (0.54) | PRSS1PRSS2PRSS3GRIN1GRIN2A | |
| SCHEMBL24179824 | 0.83 | PRSS1 (0.54) | PRSS1PRSS2PRSS3FOLH1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190127419-A1 | NEUROPEPTIDE S RECEPTOR (NPSR) AGONISTS | RESEARCH TRIANGLE INSTITUTE | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127419-A1 | NEUROPEPTIDE S RECEPTOR (NPSR) AGONISTS | NPSR1, GRPR, NPBWR1 | PRSS1 195/4885PRSS2 395/4885PRSS3 375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.