SCHEMBL209651

SCHEMBL209651

COc1ncccc1C=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.52
TRIM33 Q9UPN9 1/20 0.52
IDH1 O75874 1/20 0.48
BTK Q06187 1/20 0.46
NFE2L2 Q16236 5/20 0.46
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
APLNR P35414 1/20 0.43
ERN1 O75460 2/20 0.43
TLR2 O60603 1/20 0.43
TLR1 Q15399 1/20 0.43
TLR6 Q9Y2C9 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
KMT2A Q03164 3/20 0.41
LMNA P02545 2/20 0.41
MEN1 O00255 2/20 0.41
THRB P10828 1/20 0.41
BLM P54132 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29953915 1.00 TRIM24 (0.52) TRIM24TRIM33IDH1BTKNFE2L2
SCHEMBL30989469 0.87 TRIM24 (0.47) TRIM24TRIM33IDH1BTKNFE2L2
SCHEMBL16096639 0.82 TRIM24 (0.46) TRIM24TRIM33IDH1BTKNFE2L2
SCHEMBL6629613 0.82 IDH1 (0.46) TRIM24TRIM33IDH1BTKNFE2L2
SCHEMBL871969 0.81 ALDH1A1 (0.51) TRIM24TRIM33NPC1LMNAALDH1A1
SCHEMBL29953656 0.81 ALDH1A1 (0.51) TRIM24TRIM33NPC1LMNAALDH1A1
SCHEMBL23516654 0.80 IDH1 (0.44) TRIM24TRIM33IDH1BTKNFE2L2
SCHEMBL28151579 0.80 IDH1 (0.44) TRIM24TRIM33IDH1BTKNFE2L2
SCHEMBL28800617 0.80 IDH1 (0.44) TRIM24TRIM33IDH1BTKNFE2L2
SCHEMBL2600013 0.79 TRIM24 (0.47) TRIM24TRIM33NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116867782-A Pyrazole amide derivative 豪夫迈·罗氏有限公司 2023-10-10 CN claimed
EP-2245132-B1 ENCAPSULATED BENEFIT AGENT UNILEVER PLC NO 41424 (GB) 2017-10-18 EP claimed
CN-102015993-B Encapsulated benefit agent UNILEVER PLC 2013-03-27 CN claimed
CN-102015993-A Encapsulated benefit agent UNILEVER PLC 2011-04-13 CN claimed
EP-2245132-A1 ENCAPSULATED BENEFIT AGENT Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2010-11-03 EP claimed
WO-2009103576-A1 ENCAPSULATED BENEFIT AGENT UNILEVER PLC (GB) 2009-08-27 WO claimed
EP-3820860-B1 PYRIDAZINE COMPOUNDS FOR INHIBITING NAV1.8 LIEBER INST INC (US) 2025-10-15 EP disclosed
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 US disclosed
WO-2025106482-A1 COMPOUNDS AND COMPOSITIONS AS SMARCA2/4 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2025-05-22 WO disclosed
CN-119731185-A Synthesis of substituted 1-aryl-1 '-heteroaryl compounds and substituted 1,1' -bisheteroaryl compounds and analogs thereof 爱彼特生物制药公司 2025-03-28 CN disclosed
EP-4476204-A1 COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS Theras, Inc. (US) 2024-12-18 EP disclosed
EP-4463459-A1 STAT MODULATORS AND USES THEREOF Recludix Pharma, Inc. (US) 2024-11-20 EP disclosed
CN-118946555-A Compounds having T-structures formed by at least four rings for use in the treatment of cancer and other indications 瑟拉斯有限公司 2024-11-12 CN disclosed
US-5212317-A Methods and intermediates for the assymmetric synthesis of camptothecin and camptothecin analogs NORTH CAROLINA STATE UNIVERSITY (US) 1993-05-18 US disclosed
US-5200524-A Camptothecin intermediates and method of making same NORTH CAROLINA STATE UNIVERSITY (US) 1993-04-06 US disclosed
US-5191082-A Camptothecin intermediate and method of making camptothecin intermediates NORTH CAROLINA STATE UNIVERSITY (US) 1993-03-02 US disclosed
CN-1067656-A 2 of aminomethyl replacement, the 3-dihydropyrane is [2,3-b] pyridines also, preparation method and the application in medicine BAYER AG (DE) 1993-01-06 CN disclosed
EP-0519291-A1 Amino-methyl substituted 2,3-Dihydropyrano (2,3-b) pyridines, process for their preparation and their use in medicines BAYER AG (DE) 1992-12-23 EP disclosed
US-5162532-A INTERMEDIATES AND METHOD OF MAKING CAMPTOTHECIN AND CAMPTOTHECIN ANALOGS NORTH CAROLINA STATE UNIVERSITY (US) 1992-11-10 US disclosed
WO-1992011263-A1 METHOD OF MAKING CAMPTOTHECIN AND CAMPTOTHECIN ANALOGS NORTH CAROLINA STATE UNIVERSITY (US) 1992-07-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A TRIM24 2074/4885TRIM33 3195/4885IDH1 2882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.