SCHEMBL871969

SCHEMBL871969

CCOc1ncccc1C=O

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
GAA P10253 1/20 0.51
TRIM24 O15164 1/20 0.48
TRIM33 Q9UPN9 1/20 0.48
L3MBTL1 Q9Y468 3/20 0.43
TSHR P16473 2/20 0.41
NPC1 O15118 1/20 0.41
HPGD P15428 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
HTT P42858 1/20 0.41
MAPK1 P28482 1/20 0.40
SLC13A5 Q86YT5 2/20 0.40
LMNA P02545 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29953656 1.00 ALDH1A1 (0.51) ALDH1A1GAATRIM24TRIM33L3MBTL1
SCHEMBL3687846 0.86 TRIM24 (0.46) ALDH1A1GAATRIM24TRIM33L3MBTL1
SCHEMBL16096639 0.82 TRIM24 (0.46) ALDH1A1GAATRIM24TRIM33L3MBTL1
SCHEMBL29953915 0.81 TRIM24 (0.52) ALDH1A1TRIM24TRIM33L3MBTL1NPC1
SCHEMBL209651 0.81 TRIM24 (0.52) ALDH1A1TRIM24TRIM33L3MBTL1NPC1
SCHEMBL16305577 0.79 TRIM24 (0.46) ALDH1A1GAATRIM24TRIM33L3MBTL1
SCHEMBL17028320 0.78 ALDH1A1 (0.46) ALDH1A1GAATRIM24TRIM33L3MBTL1
SCHEMBL17063885 0.77 ALDH1A1 (0.46) ALDH1A1L3MBTL1TSHRNPC1HPGD
SCHEMBL2600011 0.77 TRIM24 (0.44) ALDH1A1TRIM24TRIM33L3MBTL1NPC1
SCHEMBL17063886 0.77 ALDH1A1 (0.46) ALDH1A1L3MBTL1TSHRNPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119318874-B Preparation method of energy-saving composite desulfurizing agent 淄博凯美可工贸有限公司 2025-04-15 CN claimed
CN-119318874-A Preparation method of energy-saving composite desulfurizing agent 淄博凯美可工贸有限公司 2025-01-17 CN claimed
EP-2245132-B1 ENCAPSULATED BENEFIT AGENT UNILEVER PLC NO 41424 (GB) 2017-10-18 EP claimed
CN-102015993-B Encapsulated benefit agent UNILEVER PLC 2013-03-27 CN claimed
CN-102015993-A Encapsulated benefit agent UNILEVER PLC 2011-04-13 CN claimed
EP-2245132-A1 ENCAPSULATED BENEFIT AGENT Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2010-11-03 EP claimed
WO-2009103576-A1 ENCAPSULATED BENEFIT AGENT UNILEVER PLC (GB) 2009-08-27 WO claimed
EP-4600247-A2 PD-1/PD-L1 INHIBITORS Gilead Sciences, Inc. (US) 2025-08-13 EP disclosed
EP-3781556-B1 PD-1/PD-L1 INHIBITORS GILEAD SCIENCES INC (US) 2025-06-18 EP disclosed
CN-119318874-B Preparation method of energy-saving composite desulfurizing agent 淄博凯美可工贸有限公司 2025-04-15 CN disclosed
CN-119318874-A Preparation method of energy-saving composite desulfurizing agent 淄博凯美可工贸有限公司 2025-01-17 CN disclosed
WO-2021126999-A1 USE OF BIOMARKERS IN IDENTIFYING PATIENTS THAT WILL BE RESPONSIVE TO TREATMENT WITH A PRMT5 INHIBITOR MERCK SHARP & DOHME CORP. (US) 2021-06-24 WO disclosed
WO-2021086044-A1 NOVEL COMPOUND FOR CROP PROTECTANT 주식회사 엘지화학 2021-05-06 WO disclosed
EP-2245132-A1 ENCAPSULATED BENEFIT AGENT Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2010-11-03 EP disclosed
WO-2010045012-A1 HETEROARYL AND PHENYL SUBSTITUTED THIENO [2,3-D] PYRIMIDINES AND THEIR USE AS ADENOSINE A2A RECEPTOR ANTAGONISTS JANSSEN PHARMACEUTICA NV (BE) 2010-04-22 WO disclosed
US-20100093722-A1 HETEROARYL AND PHENYL SUBSTITUTED THIENO[2,3-d]PYRIMIDINES AND THEIR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS JANSSEN PHARMACEUTICA NV (BE) 2010-04-15 US disclosed
WO-2009143018-A2 COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR PLEXXIKON, INC. (US) 2009-11-26 WO disclosed
US-20090286782-A1 COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR PLEXXIKON, INC. 2009-11-19 US disclosed
US-20090286782-A1 COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR PLEXXIKON, INC. 2009-11-19 US disclosed
WO-2009103576-A1 ENCAPSULATED BENEFIT AGENT UNILEVER PLC (GB) 2009-08-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100093722-A1 HETEROARYL AND PHENYL SUBSTITUTED THIENO[2,3-d]PYRIMIDINES AND THEIR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS ADORA2A, ADORA3, ADORA2B ALDH1A1 1161/4885GAA 3056/4885TRIM24 4183/4885
US-20090286782-A1 COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR PRKDC, PRKACA, PRKACG ALDH1A1 3699/4885GAA 691/4885TRIM24 1687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.