Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783991 | 0.91 | MAPK1 (0.50) | MAPK1KMT2AMEN1L3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL783922 | 0.90 | MAPK1 (0.49) | MAPK1KMT2AMEN1L3MBTL1GAA | |
| SCHEMBL21725467 | 0.88 | MAPK1 (0.48) | MAPK1KMT2AMEN1L3MBTL1GAA | |
| SCHEMBL20964536 | 0.86 | MAPK1 (0.46) | MAPK1KMT2AMEN1L3MBTL1GAA | |
| SCHEMBL10192289 | 0.85 | KMT2A (0.56) | MAPK1KMT2AMEN1L3MBTL1GAA | |
| SCHEMBL26464607 | 0.84 | MAPK1 (0.50) | MAPK1KMT2AMEN1L3MBTL1GAA | |
| Ammonia Solution, Strong SCHEMBL27649570 | 0.84 | KMT2A (0.55) | MAPK1KMT2AMEN1L3MBTL1GAA | |
| SCHEMBL6026553 | 0.83 | MAPK1 (0.55) | MAPK1KMT2AMEN1L3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL27649600 | 0.83 | KMT2A (0.53) | MAPK1KMT2AMEN1L3MBTL1GAA | |
| SCHEMBL9967732 | 0.81 | KMT2A (0.61) | MAPK1KMT2AMEN1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190127361-A1 | Therapeutic Compounds | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127361-A1 | Therapeutic Compounds | SDHA, SLC10A1, SERPINC1 | MAPK1 2069/4885KMT2A 4728/4885MEN1 179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.