Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.55 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9044676 | 0.95 | — | — | |
| Bicarbonate SCHEMBL15662074 | 0.95 | CA4 (0.50) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL15662076 | 0.95 | CA4 (0.50) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL2257748 | 0.95 | — | — | |
| Bicarbonate SCHEMBL11321204 | 0.95 | — | — | |
| Bicarbonate SCHEMBL2420 | 0.94 | — | — | |
| Bicarbonate SCHEMBL1332437 | 0.94 | — | — | |
| Bicarbonate SCHEMBL27562247 | 0.94 | CA4 (0.60) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL2558186 | 0.94 | CA4 (0.60) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL27889751 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118704017-A | Method for electrochemical synthesis of lithium hexafluorophosphate | 无锡绿能电合科技有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-118704017-A | Method for electrochemical synthesis of lithium hexafluorophosphate | 无锡绿能电合科技有限公司 | 2024-09-27 | — | — | CN | disclosed |
| WO-2023281356-A1 | SUSTAINABLE COPOLYESTER ELASTOMER COMPOSITIONS WITH IMPROVED COLOR CAPABILITY | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2023-01-12 | — | — | WO | disclosed |
| EP-4116366-A1 | SUSTAINABLE COPOLYESTER ELASTOMER COMPOSITIONS WITH IMPROVED COLOR CAPABILITY | SHPP Global Technologies B.V. (NL) | 2023-01-11 | — | — | EP | disclosed |
| CN-109809441-B | Method for improving hydrogenation efficiency of lithium carbonate | 赣州有色冶金研究所有限公司 | 2021-05-14 | — | — | CN | disclosed |
| US-10752586-B1 | Process for preparation of molindone | LUPIN LIMITED (IN) | 2020-08-25 | — | — | US | disclosed |
| US-20200262788-A1 | PROCESS FOR PREPARATION OF MOLINDONE | LUPIN LIMITED (IN) | 2020-08-20 | — | — | US | disclosed |
| EP-1989244-B1 | PROCESS FOR MAKING POLYBUTYLENE TEREPHTHALATE (PBT) FROM POLYTHYLENE TEREPHTHALATE(PET) | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2020-05-06 | — | — | EP | disclosed |
| CN-107400083-A | A kind of preparation method of 3 [2 (3 chlorphenyl) ethyl] 2 pyridine carbonitriles | 四川大学 | 2017-11-28 | — | — | CN | disclosed |
| EP-2793928-B1 | PROCESS FOR PURIFYING A SAMPLE OF H38C2 ANTIBODY | PFIZER (US) | 2017-03-15 | — | — | EP | disclosed |
| US-20090275698-A1 | Method of Making Polybutylene Terephthalate and Compositions and Articles Comprising the Same | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2009-11-05 | — | — | US | disclosed |
| EP-1989244-A1 | PROCESS FOR MAKING POLYBUTYLENE TEREPHTHALATE (PBT) FROM POLYTHYLENE TEREPHTHALATE(PET) | Sabic Innovative Plastics IP B.V. (NL) | 2008-11-12 | — | — | EP | disclosed |
| EP-1976902-A1 | PROCESS FOR MAKING POLYBUTYLENE TEREPHTHALATE (PBT) FROM POLYETHYLENE TEREPHTHALATE (PET) | GENERAL ELECTRIC COMPANY (US) | 2008-10-08 | — | — | EP | disclosed |
| EP-1976906-A2 | COPOLYETHERSTER DERIVED FROM POLYTHYLENE TEREPHTHALATE | GENERAL ELECTRIC COMPANY (US) | 2008-10-08 | — | — | EP | disclosed |
| US-20070225474-A1 | COPOLYETHERESTERS DERIVED FROM POLYETHYLENE TEREPHTHALATE | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2007-09-27 | — | — | US | disclosed |
| WO-2007106316-A1 | PROCESS FOR MAKING POLYBUTYLENE TEREPHTHALATE (PBT) FROM POLYTHYLENE TEREPHTHALATE(PET) | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2007-09-20 | — | — | WO | disclosed |
| US-20070208160-A1 | PROCESS FOR MAKING POLYBUTYLENE TEREPHTHALATE (PBT) FROM POLYETHYLENE TEREPHTHALATE (PET) | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2007-09-06 | — | — | US | disclosed |
| US-20070203253-A1 | PROCESS FOR MAKING POLYBUTYLENE TEREPHTHALATE (PBT) FROM POLYETHYLENE TEREPHTHALATE (PET) | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2007-08-30 | — | — | US | disclosed |
| WO-2007089600-A1 | PROCESS FOR MAKING POLYBUTYLENE TEREPHTHALATE (PBT) FROM POLYETHYLENE TEREPHTHALATE (PET) | GENERAL ELECTRIC COMPANY (US) | 2007-08-09 | — | — | WO | disclosed |
| WO-2007089748-A2 | COPOLYETHERSTER DERIVED FROM POLYTHYLENE TEREPHTHALATE | GENERAL ELECTRIC COMPANY (US) | 2007-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10752586-B1 | Process for preparation of molindone | DRD1, DRD4, DRD2 | CA4 1559/4885FAHD1 4635/4885MEN1 45/4885 |
| US-20200262788-A1 | PROCESS FOR PREPARATION OF MOLINDONE | DRD1, DRD4, DRD2 | CA4 1559/4885FAHD1 4635/4885MEN1 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.