Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.66 |
| ▸ | NPC1 | O15118 | 8/20 | 0.66 |
| ▸ | MAPT | P10636 | 8/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.58 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.58 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20968177 | 0.86 | NPSR1 (0.71) | SMN1; SMN2NPC1MAPTKDM4EHSD17B10 | |
| SCHEMBL3061832 | 0.85 | RAB9A (0.68) | SMN1; SMN2NPC1MAPTKDM4EHSD17B10 | |
| SCHEMBL1660913 | 0.85 | SMN1; SMN2 (0.82) | SMN1; SMN2NPC1MAPTKDM4EHSD17B10 | |
| SCHEMBL20968219 | 0.84 | MAPT (0.57) | SMN1; SMN2NPC1MAPTRAB9AHPGD | |
| SCHEMBL13417339 | 0.81 | NPC1 (0.77) | SMN1; SMN2NPC1MAPTKDM4EHSD17B10 | |
| SCHEMBL3057492 | 0.81 | RAB9A (0.74) | SMN1; SMN2NPC1MAPTKDM4EHSD17B10 | |
| SCHEMBL19766694 | 0.80 | NPC1 (1.00) | SMN1; SMN2NPC1MAPTKDM4EHSD17B10 | |
| SCHEMBL16769350 | 0.80 | NPC1 (0.68) | SMN1; SMN2NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL20968187 | 0.79 | MAPT (0.48) | SMN1; SMN2NPC1MAPTKDM4EHSD17B10 | |
| SCHEMBL20968191 | 0.78 | NR1H4 (0.59) | SMN1; SMN2NPC1MAPTHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662164-B2 | Non-beta lactam antibiotics | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2020-05-26 | — | — | US | disclosed |
| US-20190127340-A1 | NON-BETA LACTAM ANTIBIOTICS | UNIVERSITY OF NOTRE DAME DU LAC | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662164-B2 | Non-beta lactam antibiotics | OXA1L, O60361, CUTA | SMN1; SMN2 3703/4885NPC1 2521/4885MAPT 4082/4885 |
| US-20190127340-A1 | NON-BETA LACTAM ANTIBIOTICS | OXA1L, O60361, CUTA | SMN1; SMN2 3703/4885NPC1 2521/4885MAPT 4082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.