SCHEMBL20969686

SCHEMBL20969686

NCCc1ccc(OCC2CCC2)cc1

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PARP15 Q460N3 5/20 0.55
PARP10 Q53GL7 5/20 0.55
PARP2 Q9UGN5 2/20 0.55
MAOB P27338 3/20 0.47
TAAR1 Q96RJ0 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7214458 0.95 PARP10 (0.56) PARP15PARP10PARP2
SCHEMBL8070246 0.93 PARP15 (0.53) PARP15PARP10PARP2MAOBTAAR1
SCHEMBL23291223 0.83 HSP90AA1 (0.47) MAOBTAAR1
SCHEMBL2563096 0.82 PARP10 (0.62) PARP15PARP10PARP2
SCHEMBL506275 0.81 PARP10 (0.59) PARP15PARP10PARP2
Hydrochloric Acid SCHEMBL7221109 0.79 PARP10 (0.58) PARP15PARP10PARP2
SCHEMBL23642692 0.79 PARP15 (0.51) PARP15PARP10PARP2
SCHEMBL9970995 0.79 PARP15 (0.54) PARP15PARP10PARP2
SCHEMBL1391184 0.79 PARP15 (0.58) PARP15PARP10PARP2MAOB
SCHEMBL20766456 0.78 PARP15 (0.56) PARP15PARP10PARP2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3483149-B1 BENZO[D]THIAZOLE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME YUHAN CORP (KR) 2021-01-13 EP disclosed
US-10383859-B2 Benzo[d]thiazole derivative or salt thereof, and pharmaceutical composition including same YUHAN CORPORATION (KR) 2019-08-20 US disclosed
US-20190142809-A1 Benzo[D]Thiazole Derivative Or Salt Thereof, And Pharmaceutical Composition Including Same YUHAN CORPORATION (KR) 2019-05-16 US disclosed
EP-3483149-A1 BENZO[D]THIAZOLE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME Yuhan Corporation (KR) 2019-05-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190142809-A1 Benzo[D]Thiazole Derivative Or Salt Thereof, And Pharmaceutical Composition Including Same ILK, SBDS, BDKRB1 PARP15 2147/4885PARP10 2553/4885PARP2 4598/4885
US-10383859-B2 Benzo[d]thiazole derivative or salt thereof, and pharmaceutical composition including same ILK, SBDS, BDKRB1 PARP15 2147/4885PARP10 2553/4885PARP2 4598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.