Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3305583 | 0.88 | PNP (0.39) | L3MBTL1PNPKMT2AALDH1A1POLB | |
| SCHEMBL9234445 | 0.86 | PNP (0.44) | L3MBTL1PNPKMT2ATNIKALDH1A1 | |
| SCHEMBL3303803 | 0.85 | PNP (0.44) | L3MBTL1PNPKMT2AALDH1A1POLB | |
| SCHEMBL18247 | 0.85 | PNP (0.59) | PNPKMT2AALDH1A1POLBMEN1 | |
| Hydrochloric Acid SCHEMBL17186488 | 0.84 | PNP (0.43) | L3MBTL1PNPKMT2AALDH1A1POLB | |
| SCHEMBL1980958 | 0.84 | PNP (0.57) | PNPKMT2AALDH1A1POLBMEN1 | |
| SCHEMBL4966788 | 0.82 | PNP (0.44) | PNPKMT2AALDH1A1POLBMEN1 | |
| SCHEMBL17186469 | 0.82 | SOS1 (0.39) | L3MBTL1PNPKMT2AALDH1A1POLB | |
| SCHEMBL1262618 | 0.82 | PNP (0.45) | L3MBTL1PNPKMT2AALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL17186518 | 0.81 | PNP (0.44) | PNPKMT2AALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10981913-B2 | 11C -labeled 06 -benzylguanine, pet probe capable of visualizing 06-methyl guanine methyl-transferase activity, and production method of the same | NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY (JP) | 2021-04-20 | — | — | US | disclosed |
| EP-3483160-B1 | METHOD FOR PRODUCING A 11C-LABELLED O6-BENZYLGUANINE | NAT CT GERIATRICS & GERONTOLOGY (JP) | 2020-11-18 | — | — | EP | disclosed |
| US-20190308974-A1 | 11C -LABELED O6 -BENZYLGUANINE, PET PROBE CAPABLE OF VISUALIZING O6 -METHYL GUANINE METHYL-TRANSFERASE ACTIVITY, AND PRODUCTION METHOD OF THE SAME | NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY (JP) | 2019-10-10 | — | — | US | disclosed |
| EP-3483160-A1 | 11C-LABELLED O6-BENZYLGUANINE, POSITRON EMISSION TOMOGRAPHY (PET) PROBE CAPABLE OF VISUALIZING O6-METHYL GUANINE METHYL-TRANSFERASE ACTIVITY, AND PRODUCTION METHODS THEREFOR | National Center for Geriatrics and Gerontology (JP) | 2019-05-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190308974-A1 | 11C -LABELED O6 -BENZYLGUANINE, PET PROBE CAPABLE OF VISUALIZING O6 -METHYL GUANINE METHYL-TRANSFERASE ACTIVITY, AND PRODUCTION METHOD OF THE SAME | DIMT1, ICMT, NUDT1 | L3MBTL1 79/4885PNP 250/4885KMT2A 438/4885 |
| US-10981913-B2 | 11C -labeled 06 -benzylguanine, pet probe capable of visualizing 06-methyl guanine methyl-transferase activity, and production method of the same | DIMT1, MPG, NUDT1 | L3MBTL1 116/4885PNP 189/4885KMT2A 432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.