SCHEMBL20974097

SCHEMBL20974097

O=C(O)N1[C@@H]2CC(O)C[C@H]1C2

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
LMNA P02545 1/20 0.39
CYP2C9 P11712 1/20 0.39
ATM Q13315 1/20 0.30
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25395371 1.00 CHRM2 (0.39) CHRM2CHRM1CHRM3LMNACYP2C9
SCHEMBL19307797 0.87 CHRM2 (0.52) CHRM2CHRM1CHRM3LMNACYP2C9
SCHEMBL17062522 0.87 CHRM2 (0.52) CHRM2CHRM1CHRM3LMNACYP2C9
SCHEMBL19617896 0.87 CHRM2 (0.52) CHRM2CHRM1CHRM3LMNACYP2C9
SCHEMBL639674 0.87 CHRM2 (0.52) CHRM2CHRM1CHRM3LMNACYP2C9
SCHEMBL1164966 0.87 CHRM2 (0.52) CHRM2CHRM1CHRM3LMNACYP2C9
SCHEMBL19617523 0.87 CHRM2 (0.52) CHRM2CHRM1CHRM3LMNACYP2C9
SCHEMBL1164859 0.87 CHRM2 (0.52) CHRM2CHRM1CHRM3LMNACYP2C9
SCHEMBL22325361 0.86 CHRM2 (0.35) CHRM2CHRM1CHRM3LMNACYP2C9
SCHEMBL20958537 0.83 CHRM2 (0.44) CHRM2CHRM1CHRM3LMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10722514-B2 Ubiquitin-specific-processing protease 7 (USP7) modulators and uses thereof RAPT THERAPEUTICS, INC. (US) 2020-07-28 US disclosed
US-20190142834-A1 UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF RAPT THERAPEUTICS, INC. 2019-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190142834-A1 UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF USP7, SENP7, USP8 CHRM2 4685/4885CHRM1 4622/4885CHRM3 4268/4885
US-10722514-B2 Ubiquitin-specific-processing protease 7 (USP7) modulators and uses thereof USP7, SENP7, USP8 CHRM2 4685/4885CHRM1 4622/4885CHRM3 4268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.