Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CCR1 | P32246 | 3/20 | 0.48 |
| ▸ | CCR5 | P51681 | 3/20 | 0.48 |
| ▸ | CCR8 | P51685 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21931157 | 0.81 | MAPT (0.44) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL27277552 | 0.78 | LMNA (0.48) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL22214046 | 0.77 | HTR2A (0.44) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL27252002 | 0.77 | HTR2A (0.48) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL19153313 | 0.73 | CCR1 (0.42) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL23758074 | 0.73 | HTR2A (0.44) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL29845529 | 0.72 | PARP1 (0.50) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL256379 | 0.72 | PARP1 (0.50) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL13377372 | 0.71 | BRD4 (0.42) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL27262438 | 0.71 | CCR1 (0.55) | KDM4ECCR1CCR5CCR8PSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199604-A1 | SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-06-20 | — | — | US | disclosed |
| WO-2024059845-A1 | SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-03-21 | — | — | WO | disclosed |
| US-20210107896-A1 | Macrophage Migration Inhibitory Factor Inhibitors, and Methods of Making and Using Same | UNIV YALE (US) | 2021-04-15 | — | — | US | disclosed |
| US-10899739-B2 | Macrophage migration inhibitory factor inhibitors, and methods of making and using same | YALE UNIVERSITY (US) | 2021-01-26 | — | — | US | disclosed |
| US-20190144424-A1 | Macrophage Migration Inhibitory Factor Inhibitors, and Methods of Making and Using Same | YALE UNIVERSITY | 2019-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199604-A1 | SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS | MAPT, HTT, PSEN1 | KDM4E 4298/4885CCR1 693/4885CCR5 1585/4885 |
| US-20210107896-A1 | Macrophage Migration Inhibitory Factor Inhibitors, and Methods of Making and Using Same | MIF, MMP12, METAP1 | KDM4E 651/4885CCR1 309/4885CCR5 843/4885 |
| US-20190144424-A1 | Macrophage Migration Inhibitory Factor Inhibitors, and Methods of Making and Using Same | MIF, MMP12, METAP1 | KDM4E 651/4885CCR1 309/4885CCR5 843/4885 |
| US-10899739-B2 | Macrophage migration inhibitory factor inhibitors, and methods of making and using same | MIF, MMP12, METAP1 | KDM4E 651/4885CCR1 309/4885CCR5 843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.