SCHEMBL20975974

SCHEMBL20975974

CNC(C(=O)NC(C(=O)N(C)C)C(C)C)C(C)C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.32
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19155028 1.00 CNR2 (0.32) CNR2MMP9MMP8
SCHEMBL14161355 0.85 DPP4 (0.32) MMP9MMP8
SCHEMBL22901473 0.82 CNR2 (0.32) CNR2MMP9MMP8
SCHEMBL25264872 0.80 PDF (0.35) MMP9MMP8
SCHEMBL25662655 0.80 CNR2 (0.32) CNR2MMP9MMP8
SCHEMBL22661811 0.78 CNR2 (0.31) CNR2
SCHEMBL23893987 0.78 CNR2 (0.31) CNR2
SCHEMBL19784396 0.78 CNR2 (0.31) CNR2
SCHEMBL30534328 0.78 PDF (0.39)
SCHEMBL2969312 0.77 MMP9 (0.35) CNR2MMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10280229-B2 Linkers and their application towards ADC MEDSHINE DISCOVERY INC. (CN) 2019-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10280229-B2 Linkers and their application towards ADC DNPEP, DPP7, DPP3 CNR2 4290/4885MMP9 892/4885MMP8 733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.