Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 12/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.54 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18615628 | 0.85 | CXCR3 (0.57) | EPHX2CXCR3NPC1RAB9AKMT2A | |
| SCHEMBL20976418 | 0.82 | EPHX2 (0.65) | EPHX2EPHX1CXCR3NPC1RAB9A | |
| SCHEMBL20976436 | 0.80 | EPHX2 (0.46) | EPHX2CXCR3ABL1KCNH2 | |
| SCHEMBL29739488 | 0.77 | ABL1 (0.55) | EPHX2NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL31441055 | 0.77 | ABL1 (0.55) | EPHX2NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL26739652 | 0.76 | ABL1 (0.49) | EPHX2NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL12196159 | 0.72 | EPHX2 (1.00) | EPHX2EPHX1NPC1RAB9A | |
| SCHEMBL29177190 | 0.71 | ABL1 (0.50) | EPHX2ABL1KCNH2KDM4E | |
| SCHEMBL20976417 | 0.71 | EPHX2 (0.50) | EPHX2 | |
| SCHEMBL13663053 | 0.70 | CXCR3 (0.67) | EPHX2CXCR3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10280145-B2 | Urea derivative and use therefor | TORAY INDUSTRIES, INC. (JP) | 2019-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10280145-B2 | Urea derivative and use therefor | UTS2R, DDR1, WEE1 | EPHX2 4826/4885EPHX1 4496/4885CXCR3 2718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.