Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29177240 | 0.83 | EPHX2 (0.52) | ABL1ALDH1A1EPHX2KDM4ETSHR | |
| SCHEMBL29177322 | 0.83 | ALDH1A1 (0.45) | ABL1KCNH2ALDH1A1AOC3HPGD | |
| SCHEMBL27292140 | 0.81 | KCNH2 (0.47) | ABL1KCNH2MGLLALDH1A1HPGD | |
| SCHEMBL29177219 | 0.78 | CNR2 (0.47) | ABL1KCNH2MGLLKCNJ1 | |
| SCHEMBL29115151 | 0.76 | SMN1; SMN2 (0.60) | AOC3HPGDKDM4EHIF1AEPAS1 | |
| SCHEMBL29177263 | 0.76 | ALDH1A1 (0.53) | ABL1KCNH2ALDH1A1KCNJ1HPGD | |
| SCHEMBL30695916 | 0.76 | ALDH1A1 (0.53) | ABL1KCNH2ALDH1A1KCNJ1HPGD | |
| SCHEMBL31441055 | 0.75 | ABL1 (0.55) | ABL1KCNH2ALDH1A1EPHX2HPGD | |
| SCHEMBL29739488 | 0.75 | ABL1 (0.55) | ABL1KCNH2ALDH1A1EPHX2HPGD | |
| SCHEMBL26739652 | 0.75 | ABL1 (0.49) | ABL1KCNH2MGLLALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242060-A | Isoindolinone compounds | 蒙特罗萨医疗公司 | 2023-12-15 | — | — | CN | disclosed |