Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16070739 | 0.89 | IGF1R (0.43) | IGF1RCXCR3ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL12222364 | 0.84 | LMNA (0.48) | SMN1; SMN2ALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL16070680 | 0.84 | KMT2A (0.36) | IGF1RSMN1; SMN2CXCR3L3MBTL1MEN1 | |
| SCHEMBL16070677 | 0.80 | AOC3 (0.33) | ALDH1A1KDM4EPOLB | |
| SCHEMBL18530454 | 0.78 | LMNA (0.43) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL26988688 | 0.74 | IGF1R (0.39) | IGF1RCXCR3ALDH1A1MEN1KMT2A | |
| SCHEMBL8340734 | 0.73 | CYP3A4 (0.34) | ALDH1A1KDM4E | |
| SCHEMBL7541159 | 0.72 | TSHR (0.39) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9343488 | 0.71 | ALDH1A1 (0.33) | SMN1; SMN2NPC1THRBRAB9AALDH1A1 | |
| SCHEMBL28423888 | 0.71 | ALDH1A1 (0.41) | SMN1; SMN2NPC1THRBRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975022-B1 | NOVEL HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF | FUJIFILM TOYAMA CHEMICAL CO LTD (JP) | 2019-05-08 | — | — | EP | disclosed |