Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903598 | 0.79 | BCL2L1 (0.38) | SMN1; SMN2BCL2L1BADMEN1KMT2A | |
| SCHEMBL31401385 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2ARXRARXRB | |
| SCHEMBL903596 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2ARXRARXRB | |
| SCHEMBL23860824 | 0.76 | NOS3 (0.46) | SMN1; SMN2MEN1KMT2AACHEMAPT | |
| SCHEMBL30133422 | 0.76 | NOS3 (0.46) | SMN1; SMN2MEN1KMT2AACHEMAPT | |
| SCHEMBL25238832 | 0.75 | SMN1; SMN2 (0.38) | SMN1; SMN2RXRARXRBPPARGRXRG | |
| SCHEMBL25433645 | 0.72 | ACHE (0.39) | SMN1; SMN2ACHEALDH1A1BCHECHRM1 | |
| SCHEMBL30667978 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL30496070 | 0.72 | ACHE (0.39) | SMN1; SMN2ACHEALDH1A1BCHECHRM1 | |
| SCHEMBL26684739 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EALDH1A1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3480198-B1 | NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | RIKEN (JP) | 2021-05-05 | — | — | EP | disclosed |
| EP-3480198-A1 | NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | RIKEN (JP) | 2019-05-08 | — | — | EP | disclosed |