Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 11/20 | 0.75 |
| ▸ | DGAT1 | O75907 | 9/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22712914 | 0.86 | FOLH1 (1.00) | FOLH1DGAT1 | |
| SCHEMBL14722195 | 0.86 | FOLH1 (1.00) | FOLH1DGAT1 | |
| SCHEMBL18161528 | 0.86 | FOLH1 (1.00) | FOLH1DGAT1 | |
| SCHEMBL14722192 | 0.86 | FOLH1 (1.00) | FOLH1DGAT1 | |
| SCHEMBL19248267 | 0.86 | DGAT1 (0.64) | FOLH1DGAT1 | |
| SCHEMBL29293807 | 0.86 | DGAT1 (0.64) | FOLH1DGAT1 | |
| SCHEMBL14721856 | 0.86 | FOLH1 (0.91) | FOLH1DGAT1 | |
| SCHEMBL24703367 | 0.86 | FOLH1 (0.68) | FOLH1DGAT1 | |
| SCHEMBL22957840 | 0.85 | DGAT1 (0.79) | FOLH1DGAT1 | |
| SCHEMBL25897923 | 0.85 | DGAT1 (0.79) | FOLH1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057991-B1 | CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RES (US) | 2019-05-08 | — | — | EP | disclosed |