SCHEMBL24703367

SCHEMBL24703367

O=C(O)CC[C@H](NC(=O)N[C@@H](CCCCn1cc(CCCCCCNC(=O)c2ccccc2)nn1)C(=O)O)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 14/20 0.68
▸ DGAT1 O75907 6/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18359218 0.89 DGAT1 (0.70) FOLH1DGAT1
SCHEMBL29293807 0.88 DGAT1 (0.64) FOLH1DGAT1
SCHEMBL19248267 0.88 DGAT1 (0.64) FOLH1DGAT1
SCHEMBL19248901 0.87 DGAT1 (0.63) FOLH1DGAT1
SCHEMBL17706050 0.87 FOLH1 (0.62) FOLH1DGAT1
SCHEMBL16666080 0.87 FOLH1 (0.62) FOLH1DGAT1
SCHEMBL17706042 0.87 DGAT1 (0.63) FOLH1DGAT1
SCHEMBL25681677 0.86 DGAT1 (0.62) FOLH1DGAT1
SCHEMBL20979154 0.86 FOLH1 (0.75) FOLH1DGAT1
SCHEMBL17037348 0.85 DGAT1 (0.65) FOLH1DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220396621-A1 TARGETING AGENT ANTIBODY CONJUGATES AND USES THEREOF SCRIPPS RESEARCH INST (US) 2022-12-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220396621-A1 TARGETING AGENT ANTIBODY CONJUGATES AND USES THEREOF CD22, FCGR2A, CD47 FOLH1 226/4885DGAT1 2892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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