Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 6/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | TLR9 | Q9NR96 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | STAT3 | P40763 | 4/20 | 0.58 |
| ▸ | STAT1 | P42224 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | MITF | O75030 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 8/20 | 0.57 |
| ▸ | HPGD | P15428 | 7/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | BID | P55957 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3564044 | 0.75 | KDM4E (0.67) | NPSR1SMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL3557132 | 0.75 | KDM4E (0.71) | NPSR1SMN1; SMN2LMNATLR9KDM4E | |
| SCHEMBL4721292 | 0.74 | SDHB (0.81) | SDHBNPSR1SMN1; SMN2LMNATLR9 | |
| SCHEMBL19805808 | 0.74 | SDHB (1.00) | SDHBNPSR1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL19805673 | 0.73 | SDHB (1.00) | SDHBNPSR1SMN1; SMN2LMNATLR9 | |
| SCHEMBL19805665 | 0.73 | NPSR1 (1.00) | SDHBNPSR1SMN1; SMN2LMNATLR9 | |
| SCHEMBL19805844 | 0.73 | SDHB (1.00) | SDHBNPSR1SMN1; SMN2LMNATLR9 | |
| SCHEMBL13912197 | 0.73 | NPSR1 (1.00) | SDHBNPSR1SMN1; SMN2LMNATLR9 | |
| SCHEMBL19805811 | 0.72 | SDHB (0.71) | SDHBNPSR1SMN1; SMN2LMNATLR9 | |
| SCHEMBL29975914 | 0.71 | NPSR1 (1.00) | SDHBNPSR1SMN1; SMN2LMNATLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190134214-A1 | GLP-1 Receptor Ligand Moiety Conjugated Oligonucleotides and Uses Thereof | ASTRAZENECA AB (SE) | 2019-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190134214-A1 | GLP-1 Receptor Ligand Moiety Conjugated Oligonucleotides and Uses Thereof | GLP1R, GIPR, GRPR | SDHB 4881/4885NPSR1 83/4885SMN1; SMN2 3594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.