Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23321177 | 0.89 | ITGB3 (0.53) | ITGB3ITGA2B | |
| SCHEMBL27822202 | 0.86 | PRMT5 (0.47) | ITGB3ITGA2B | |
| SCHEMBL15939257 | 0.85 | ITGB3 (0.50) | ITGB3ITGA2B | |
| SCHEMBL7796015 | 0.84 | ITGB3 (0.60) | ITGB3ITGA2B | |
| SCHEMBL7797432 | 0.83 | ITGB3 (0.63) | ITGB3ITGA2B | |
| SCHEMBL4881755 | 0.83 | ITGB3 (0.59) | ITGB3ITGA2B | |
| SCHEMBL14061622 | 0.82 | AOC3 (0.60) | ITGB3ITGA2B | |
| SCHEMBL29505381 | 0.82 | AOC3 (0.60) | ITGB3ITGA2B | |
| SCHEMBL30530638 | 0.81 | AOC3 (0.48) | ITGB3ITGA2B | |
| SCHEMBL25362979 | 0.81 | AOC3 (0.48) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107567443-B | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2023-04-28 | — | — | CN | disclosed |
| US-10669252-B2 | Benzazepine derivative, preparation method, pharmaceutical composition and use thereof | Shanghai De Novo Pharmatech Co., Ltd. (CN) | 2020-06-02 | — | — | US | disclosed |
| US-20190152941-A1 | BENZAZEPINE DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai De Novo Pharmatech Co., Ltd. (CN) | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10669252-B2 | Benzazepine derivative, preparation method, pharmaceutical composition and use thereof | TLR8, TLR1, TLR5 | ITGB3 3015/4885ITGA2B 3930/4885 |
| US-20190152941-A1 | BENZAZEPINE DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | TLR8, TLR1, TLR5 | ITGB3 3015/4885ITGA2B 3930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.